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- Higuchi模型Higuchi
- Higuchi方程Higuchi Equation
- 释放分割法体外评价释放特征符合Higuchi方程的缓释制剂药物动力学The Release-Division method: a novel in vitro pharmacokinetic evaluation method for the sustained release dosage forms with a release profile characterized by the Higuchi equation
- 用优化的处方 ,工艺制备的三批卡托普利缓释片体外释放良好 ,符合 Higuchi方程 ,持续释药 12 h以上Three bates of Cap sustained release tablets prepared according to this optimal formulation and technology conform to Higuchi equation and the drug can be sustainedly released over 12 h in vitro .
- 初步考察了AMSA-SLN的体外释药过程，释放曲线经拟合后符合Higuchi方程，药物释放初期有突释现象，随后药物呈现持续而缓慢的释放。The quality of the AMSA-SLN suspension was evaluated before and after freeze-drying.
- 然后将测压管拉出20cm,继续同样的测量并得出结肠压力数据,采用Higuchi算法计算肠道压力的分形维,通过分形维来区分正常的和异常的结肠压力信号。Fractal dimension of intestinal tract pressure was calculated with the method from Higuchi to distinguish normal and abnormal colonic pressure signal.
