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- Hepatic stellate cells activated and proliferated. 贮脂细胞活化、增殖。
- Activation of hepatic stellate cell (HSC) has become the cellular basis for hepaticfibrogenesis. 肝星状细胞(HSC)的活化是肝纤维化发生、发展的细胞学基础。
- Objective:To study the effects of bupleurum on collagen degradation of hepatic stellate cell in vitro. 目的:观察柴胡对肝星形细胞有关胶原降解基因表达的影响。
- Aim The effect of compound 861(Cpd 861) on rat hepatic stellate cell(HSC) proliferation and collagen synthesis in vitro was observed. 目的观察中药复方861对体外培养肝星状细胞增殖及胶原合成的影响。
- Conclusion: Inhibition of hepatic stellate cell proliferation and collagen synthesi s may be one important mechanism of hepatoprotective and antifibrotic properties of silibinin. 结论:抑制贮脂细胞增殖和胶原合成可能是水飞蓟宾保护肝脏抗硬化机制之一。
- XBR can prevent the occurrence and development of hepatic fibrosis in rats,the effect may be related to its preventing liver cell against injury,inhibiting the synthesis of extracellular matrix(ECM) and the activation of hepatic stellate cell(HSC). 消瘢方能有效预防肝纤维化的发生、发展,其作用可能与保护肝细胞,抑制细胞外基质合成及HSC活化有关。
- International Hepatology: Besides the important role of hepatic stellate cell in liver fibrosis development， are there any other important mechanisms involving liver fibrosis development? 国际肝病：除了肝星状细胞在肝纤维化发生中的重要作用，还有哪些机制参与了肝纤维化的发生？
- HC may induce fibrogenesis directly by hepatic stellate cell actiation or indirectly by promoting oxidatie stress and apoptosis of infected cells. 慢性丙型肝炎可能通过肝脏星形胶质细胞的活化、或者间接通过促进氧化应激和受感染细胞的凋亡，直接诱导纤维形成。
- Recently, a lot of data indicate hepatic stellate cells (HSC) is the key cell of formation of ECM and HSC is also the core link of occurrenc of hepatic fibrosis. 现已证实,肝星形细胞(hepatic stellate cell,HSC)是肝脏产生 ECM 的主要细胞,HSC 活化是肝纤维化发生的中心环节。
- An effective method of isolating and culturing human hepatic stellate cells ZHANG Wen-wei, XU Lie-ming. 分离和提纯；细胞培养，方法;人肝星状细胞
- We know that hepatic stellate cells are still the major source of extracellular matrix during fibrogenesis. 我们知道肝星状细胞还是纤维化过程中细胞外基质的主要来源。
- It is well known that the activation of hepatic stellate cells (HSCs) is the key event in the process of hepatic fibrosis. 肝星状细胞(hepatic stellate cells,HSCs)的活化被认为是这一过程中的关键事件。
- After using drugs,the hepatic mitochondrion and rough EM proliferated;hepatic stellate cells and collagenous fibers reduced obviously. 应用药物防治后，肝细胞线粒体、粗面内质网增生，贮脂细胞和胶原纤维数量明显减少。
- Objective:To investigate the effects of salidroside on proliferation and extracellular matrix secretion of rat hepatic stellate cells in vitro. 目的:观察红景天苷对大鼠肝星状细胞增殖及细胞外基质分泌的影响。
- It can be concluded that CTGF was mainly produced in hepatic stellate cells, sinusoidal endothelial cells and fibroblasts. 肝星状细胞、成纤维细胞和窦状隙内皮细胞是肝内CTGF的重要来源。
- Hepatic stellate cells (HSteC) are intralobular connective tissue cells presenting myofibroblast-like or lipocyte phenotypes. 肝脏星形细胞是小叶内结缔组织细胞，呈现肌成纤维细胞样或脂肪细胞形态。
- After using drugs, the hepatic mitochondrion and rough EM proliferated;hepatic stellate cells and collagenous fibers reduced obviously. 应用药物防治后，肝细胞线粒体、粗面内质网增生，贮脂细胞和胶原纤维数量明显减少。
- Objective: To study the changes of extracellular signal - regulated kinase (Erie) in hepatic stellate cells (HSC) stimulated by acetaldehyde and its effects on HSC proliferation. 目的:探讨乙醛激活HSC过程中Erk的变化,以及阻断Erk信号传导通路对HSC增殖的影响。
- CTGF was mainly expressed in portal tracts and fibrotic areas.Positive staining was observed in hepatic stellate cells, sinusoidal endothelial cells and fibroblasts. CTGF的表达主要集中于汇管区和纤维化区，肝星状细胞、成纤维细胞和窦状隙内皮细胞染色常呈阳性。
- AIM: To investigate the effect of Baoganning (BGN) on the proliferation of hepatic stellate cells (HSCs) stimulated by leptin and its relevant mechanisms. 目的:观察中药复方保肝宁对瘦素刺激的肝星状细胞(Hepatic stellate cells,HSCs)增殖功能的影响及其发生的可能机制。
