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- HBV specific CTL HBV特异性细胞毒T细胞
- Variations of HBV can affect the reaction of specific CTL 乙型肝炎病毒变异对其特异性CTL反应的影响
- Study on Mechanism of Specific CTL Response to HBV Infection 乙肝病毒感染的特异性CTL应答机制研究
- Flow cytometry analysis indicated that the tetramer could bind to specific CTL from HLA-A11+ donor. 流式细胞仪分析显示所制备的四聚体可与HLA-A11+供者的抗原特异性CTL结合。
- The therapeutic vaccine could induce strong specific CTL activity in HLA-A2 transgenic mice. 其在HLA-A2转基因鼠中可诱导出强的表位特异性细胞毒性T淋巴细胞活性。
- In patients with chronic infection, HBV specific T cell responses are functionally impaired and we believe that this is a very important cause of chronic evolution of infection. 有慢性感染特别是HBV感染的患者，T细胞应答在功能上受损，我们认为这是感染慢性进展非常重要的原因之一。
- The specific CTL cell mediated immune responses induced by live attenuated and inactivated Japanese encephalitis(JE) vaccine in mice were compared. 应用检测特异性CTL活性的方法检测乙脑活疫苗的细胞免疫应答 ,并以灭活疫苗作对照。
- CT26 colorectal adenocarcinoma-bearing mice model were established and treated with the tumor specific CTL, the tumor size and the survival period of mice were monitored. 建立CT26荷瘤小鼠模型,应用CTL治疗荷瘤小鼠,观察肿瘤大小和小鼠存活期。
- Suppression of allo-specific CTL activity in allo-TCV immunized mice; the activity of specific CTL to alloantigen generated by in vitro bulk MLR in TCV group was much lower than that in. 在CML实验里,同种抗原特异TCV免疫小鼠的脾细胞体外诱导同种CTL活性明显受到抑制,CTL 活性十分低下。
- The tumor specific CTL was generated form activated autologous T cell by DC vaccine loaded with tumor antigen, and the killing activity of CTL to CT26 cells was tested by the lactate dehydrogenase (LDH) release assay in vitro. 负载肿瘤抗原的DC疫苗激活同源T淋巴细胞产生细胞毒性T淋巴细胞(CTL),采用乳酸脱氢酶(LDH)4h释放法检测CTL在体外对CT26细胞的杀伤活性;
- The mature DCs were co-cultured with autologous T cells to obtain antigen specific CTL (Ag-CTL) and antigen non-specific CTL (non Ag-CTL). The phenotypes of Ag-CTL were analyzed by flow cytometry. 成熟DCs与自体T细胞共育,分别获得Ag-CTL及non-Ag-CTL,流式细胞仪检测Ag-CTL细胞表型的变化;
- Tumor antigen specific CTLs may prevent metastasis in the LCI-D20 model and prolong the survival time. 肿瘤抗原特异性CTL可以预防LCI-D20模型肝癌发生转移,延长动物存活时间。
- In ABM, the remarkably increased expression of co stimulatory molecule CD86 in CD3 - MNC may enhance the anti tumor effect of antigen specific CTLs. ABM中CD3-细胞表面共刺激分子CD86表达明显增加 ,与ABM中特异性细胞毒性T淋巴细胞(CTLs)的生成有关。
- Keywords tetramer;expression;purification;refolding;specific CTL; 关键词四聚体;表达;纯化;特异性CTL;
- For either HIV-1B or HIV-1C, Gag and Nef were preferentially targeted by HIV-1 specific CTLs, Rev and Tat proteins were also recognized to different extent. 无论HIV- 1B亚型还是HIV- 1C亚型所构建肽库的应答强度和频率, 主要集中在Gag和Nef蛋白, Tat和Rev蛋白也有不同程度的应答。
- Education should not be restricted to any one specific age group. 教育不应限制在任何特定的年龄组上。
- He gave us very specific instructions. 他给我们做了非常明确的指示。
- Study on the specific CTL induced by DC loaded with lung cancer soluble antigen 肺癌可溶性抗原致敏的DC诱导CTL特异性杀伤肺癌细胞的实验研究
- There is a specific tool for each job. 各工种配备特定的工具。
- But that all depend on the specific circumstances. 不过，那要看具体情况而定。
