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- Methods Type specific primers and PCR were used to detect the HBV genotypes of 127 Uighur CHB patients in Xinjiang. 方法采用型特异性引物巢式PCR法对127例维吾尔族慢性乙型肝炎患者进行基因分型,并测序验证。
- The aim of study was to investigate the relationships between HBV genotypes (B, C), core-promoter (CP) and precore mutants and liver histology in 66 patients. 本研究的目的是对66位患者进行了HBV基因型（B、C）、核心启动子和前核心启动子突变和肝组织学之间的关系。
- Logistic regression analyses was used to identify the variables of hepatitis B e antigen (HBeAg) and the amino acid changes in HBx,Enh2 and Bcp impacting on the relationship between HBV genotypes with HCC. 应用logistic回归方法分析e抗原状况与X基因、Enh2、Bcp氨基酸位点变异等乙肝病毒学的变量对HBV基因型与HCC之间关系的影响因素。
- HBV DNA level extremly decreased after Luminvudine therapy. The appearance of HBV YMDD mutants also connected with HBV genotypes,and 80%(4/5) of them accompanied by BCP double mutations. 口服拉米夫定可以明显降低HBV水平 ,HBVYMDD突变株的发生也与基因型有关 ,且 80%25 (4 5 )伴有BCP双突变
- HBV genotypes were determined by type-specific primers PCR method. PreC/BCP mutations were detected by direct sequencing of PCR products,and Clustal W 1.8 software was applied to analyzing the sequences. 以型特异性引物PCR法检测16对乙肝疫苗阻断失败的母婴和88例阻断成功的母亲血清样本中HBV基因型;用PCR产物直接测序法检测HBV前C/ BCP突变;采用Clustal W 1.;8软件进行序列分析。
- Multiplex PCR showed that HBV-Brandt is HBV genotype A. Multiplex PCR基因型鉴定表明HBV-Brandt属于乙型肝炎病毒A型。
- On the other hand, we detected a part of them (22 ASC, 30 CHB) HBV-DNA level and HBV genotype. PCR荧光定量HBV-DNA检测。 80例中,病理G/S诊断,HBV基因型及HBV-DNA定量结果三项完整者共52例,其中ASC22例,CHB30例。
- The sequence analysis showed that all five sequences belonged to HBV genotype B,four sequences were adw serotype and one was adr serotype. 序列分析显示该 5株HBV均为B基因型 ,其中 4株为adw亚型 ,1株为adr亚型 ;
- HBV DNA level,HBV genotyping,and BCP and YMDD mutants were detected with the method of PCR microplate hybridization ELISA before and after 6 months Lumivudine therapy. 采用PCR微板核酸杂交ELISA技术分别对服药前及服药后 6个月进行HBV含量、基因型、BCP突变株及YMDD突变株的检测。
- The difference of HBV genotype may not be caused by sex. In the patient of CHB, genotype C can easily cause serious disease of liver and genotype B can easily occur immune escape which resulted in slight state of an illness. 在CHB患者中,性别不是基因型构成差别的因素,C基因型易引起较重的肝脏病变,B型易发生免疫逃逸,致病情较轻。
- In addition, other risk factors include HBV genotype C infection, male sex, older age, family history positive for hepatocellular carcinoma, and coinfection with hepatitis C virus or HIV. 此外，其他风险因素包括HBV C基因型感染、男性、年长、家族肝细胞癌病史、同时感染C型肝炎病毒或者HIV。
- Since hepatitis B virus (HBV) genotype is an important predictor of response to PEG-IFN, determination of HBV genotype is essential in patients in whom sustained off-treatment response is pursued. 由于乙肝病毒（HBV）基因型是干扰素应答的重要预测指标，测定乙肝病毒基因型对于追求治疗停止后持久应答的患者是至关重要的。
- Distribution of HBV Genotypes in Asymptomatic HBV Carriers, Chronic HB and Cirrhosis Patients 乙型肝炎病毒基因型在无症状感染者、慢性乙肝和肝硬化患者中分布研究
- Distribution of HBV genotypes in Shandong province and it's relationship with the antiviral effect of lamivudine 山东地区HBV基因型分布及拉米夫定抗病毒治疗对基因分型的影响
- Keywords Primary hepatic carcinoma（HCC）;Sero-markers of hepatitis B（ HBVM）;Hepatitis B virus（HBV）;Gastroenterol malignant tumour;Integration;HBV genotypes; 原发性肝癌;乙型肝炎病毒血清学标记;乙型肝炎病毒;消化道恶性肿瘤;整合;乙型肝炎病毒基因型;
- The HBV Genotype of Children Living in Guangzhou 广州地区小儿无症状乙肝病毒携带者的基因型研究
- HBV genotypes 肝细胞癌
- Gene chip technique for the detection of HBV genotypes and YMDD mutations is reliable and its specificity is high,it can give more information in one test and could be used for clinical application,but it is needed to improve the sensitivity; 基因芯片检测HBV基因型及HBV P基因区YMDD变异准确性高、特异性好,同时每次实验得到的信息量多,适合于临床开展应用,但需提高灵敏度;
- HB genotypes had no effect on the iremia profiles. 乙肝基因型对病毒表达谱无影响.
- Utilizing the consultive plates of genotype to analyze the HBV genotypes of Kelamayi area 利用基因参照品图谱分析克拉玛依地区HBV基因型
