Experimental studies revealed that tumor cells in a prevascular state may repli-cate as rapidly as those in an expending vascularized tumor, but the generation of new cells is balanced by dying tumor cells ( e. g. apoptosis of individual cells).

• 实验性研究发现，肿瘤细胞在血管生成前期和血管生成期的复制速度一样快，但前者由于死亡的肿瘤细胞多，因而使肿瘤细胞数量处于动态平衡状态。