Enhanced expression of HSP70 may be an important mechanism leading to enhanced survival.These dates indicate that Gln may be useful in prevention of hyperoxia lung injury.

• 结论：大鼠腹腔注射谷氨酰胺可增加肺组织热休克蛋白70表达，对高氧环境中的大鼠有保护作用，可明显地提高大鼠在高氧环境下的存活率。