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- Methods PCR-SSCP was employed to detect EGFR mutation in 36 samples with lung cancer. 方法应用PCR-SSCP检测36例肺癌标本的突变情况并与其它文献进行比较。
- The research team concluded that the particular EGFR mutation within tumor cells determines which inhibitor molecules are likely to be able to slow or stop the growth of those cells. 该研究小组总结认为,这些肿瘤细胞内特殊的EGFR突变确定了抑制剂分子可能可以减慢或者停止那些细胞的生长。
- We detected the T790M mutation, which confers drug resistance, in circulating tumor cells collected from patients with EGFR mutations who had received tyrosine kinase inhibitors. 在从接受酪氨酸激酶抑制剂治疗患者中收集的循环肿瘤细胞中,我们检测到了引起耐药的T790M突变,
- Therefore, it would also provide necessary evidence to test EGFR mutations for the use of Gefitinib in CRCs. 因此,检测大肠癌EGFR外显子突变也为将吉非替尼疗应用于大肠癌提供理论依据。
- In multivariate analysis, the presence of EGFR deletion exon 19 or L858R EGFR mutations in adenocarcinoma patients predicted longer TTF. 多因素分析提示,EGFR外显子19缺失或L858R突变的腺癌患者,是影响治疗失败时间的有利因素(延长治疗失败时间)。
- High copy number of MET seemed to correlate with shorter TTF in patients with gefitinib-sensitive activating EGFR mutations. 对于吉非替尼敏感性激活EGFR突变患者,MET基因的高拷贝数可能是影像治疗失败时间的不利因素(缩短治疗失败时间)。
- A total of 2281 patients with NSCLC were screened for EGFR mutations in their tumors and, of this group, 327 had mutations. 对总共2281名NSCLC患者肿瘤组织进行EGFR变异筛查。在这些患者中,327例患者检测到变异。
- However, patients with tumor-only EGFR mutations had longer progression-free survival than patients with mutations in both tumor tissue and serum (17 months vs 12 months). 然而,那些只有肿瘤组织中发现EGFR变异的患者与那些在肿瘤组织和血浆中都发现EGFR变异的患者的无瘤生存期更加长久(17个月相对12个月)。
- Our teacher has mutation of sounds suddenly. 我们的老师突然语音发生了变化。
- Zhang XT.Li LY.Mu XL The EGFR mutation and its correlation with response of gefitinib in previously treated Chinese patients with advanced non -small -cell lung cancer 2005 管忠震.;张力
- EGFR mutation 表皮生长因子受体突变
- Formation or development of a mutation. 变异的形成或者发展
- To undergo or cause to undergo mutation. 经历变化或使经历变化
- Mutation are produced by a number of chemicals. 许多化学试剂能产生突变。
- What matter is not innovation, but useful mutation? 二.;任何领域都可以创新三
- A new breeding method of space mutation. 一种航天育种的方法。
- High sense mutation of HVR 1 gene was found. (4)HVR1基因有义突变率相当高。
- BCP mutation may impair HBeAg expression. BCP双突变对HBeAg的表达有一定影响 ;
- Ion beam mutation has significant bio-effect. 摘要离子诱变具有显著的生物学效应。
- It is a missense mutation in exon III. 它是位于外显子III的错义突变。