During acute rejection, apoptosis of ECs is significantly increased and maybe the major cause of the endothelial-cell immunologic injury.

• 异体肢体移植术后急性排斥反应阶段,血管内皮细胞凋亡活性明显增高,提示细胞凋亡是大鼠肢体移植急性排斥反应期血管内皮细胞免疫损伤的主要原因之一。