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- Standardize and limit the number of drug concentrations used by the organization. 限定医院内同一药品不同浓度之品项数并订定规范。
- Rapamycin is a critical-dose drug requiring at least monthly monitoring of drug concentrations in the blood. 雷帕霉素是一种临界剂量药物,用药后至少需要每月监测血液中药物的浓度。
- Methods: The serum drug concentrations of 801 epileptic patients taking first-line antiepileptics were collectd and sorted.The results were analyzed. 方法:对801例服用一线抗癫癎药物病人的血药浓度进行分类汇总,并对结果进行统计学分析。
- At high drug concentrations, the amount of bound drug approaches an upper limit depending on the number of available binding sites, resulting in saturability. 药物浓度高时,因蛋白可结合部位数目的关系,结合药物量接近上限,导致饱和性。
- But at nanomolar drug concentrations, taxol exhibited effects similar to those of nanomolar concentrations of colchicine and the vinca alkaloids, in that it suppressed microtubule dynamics. 但是研究表明,当浓度为纳摩尔级时,紫杉醇显示了与同样浓度的秋水仙素、长春花类生物碱等相似的效果,即通过阻止微管蛋白聚合成微管而发挥作用。
- While median PSA leels were lower and showed higher median free/total ratios among users of both statins and fibrates, no correlations were seen between the drug concentrations and PSA leels. 虽然他汀类或贝特类降脂药能适当降低PSA水平和游离PSA/总PSA值,但降脂药的浓度和PSA水平间无相关性。
- The drug concentration in liver, kidney and plasma was determined by HPLC. 采用HPLC法测定大鼠肝、肾和血浆中的药物浓度。
- Drug concentration was measured by HPLC and the apparent permeability coefficients( P_ app) were calculated. 用高效液相色谱法检测药物浓度,计算其表观渗透系数。
- The serum drug concentrations of patients treated with combination of drugs were significantly higher than those treated with single antiepileptic (P<0.01), especially PHT/CBZ regimen. 多药联用血药浓度升高的病例增加(P<0.;01),以PHT/CBZ方案最为突出。
- We found that, a transient higher blood drug concentration(BDC) was produced by artery perfusion. 结果表明动脉灌注法可以产生局部较高的血药浓度,但维持时间较短;
- The results of HPLC showed that pharmacological effect of prodigiosin dependent on drug concentration in cells. HPLC结果显示,灵菌红素的药理学作用与细胞内药物浓度相关。
- Methods: The factors that made the determined plasma drug concentration changed on the course of TDM were analyzed. 方法:针对分析前、分析中、分析后的主要环节可能产生血药浓度变化的因素进行分析。
- The nurse diluted the drug with saline water. 护士用生理盐水把药加以稀释。
- The schizont inhibited rates increased in keeping with the increase of drug concentration. 疟原虫抑制率亦与氯喹板及阿莫地喹板相似,均随药物浓度的增高而依次上升。
- Objective: To monitor the blood drug concentration to adjust the dosage for individual administration. 目的:了解老年患者体内茶碱血药浓度,以便调整用药方案。
- METHODS PEG400,PEG6000 were used as suppository base and the drug concentration was determined by UV-spectrophotometry. 方法以PEG400,PEG6000为基质,熔融法制备奥硝唑栓剂,采用紫外分光光度法测定其含量。
- OBJECTIVE:To study the correlation between salivary drug concentration and blood,drug level its clinic sig-nificance. 目的:探求唾液药物浓度与血药浓度的相关性及临床意义。
- Objective Routine concentration of antiepileptic in plasma was determined,in order to explore the relation between drug concentration and age,sex. 目的测定癫病人血中抗癫药物的浓度,以便探讨药物浓度与年龄、性别的关系。
- METHODS:The salivary drug concentration and blood drug level of gentamicin of15volunteer cases were deter-mined by radioimmunoassay. 方法:采用放射免疫法测定15例志愿受试者庆大霉素的唾液药物浓度和血药浓度。
- Method: Drug concentration of TFH and TFH-SLN in blood, heart, liver, spleen and kidney of mice after oral administration was determined by HPLC. 方法:采用HPLC法测定小鼠口服醋柳黄酮(TFH)和TFH-SLN后血液、心、肝、脾、肾的药物浓度。
