CpG-DNA could significantly reduce activity of NAGase in mammary gland at 48 h and 72 h postinfection and concentration of albumin in mammary gland at 8 h and 72 h postinfection.

• CpG-DNA能显著降低48和72h乳腺组织NAGase活力,并极显著降低8和72h乳腺白蛋白浓度。