Conclusion Low level of IL 2 production and IL 2R expression under the HBsAg stimulation may contribute to the failure of immunization in HBV infected children.

• 结论IL-2分泌能力低下，以及IL-2膜受体表达不足可能是宫内感染HBV导致乙肝疫苗免疫失败的机制之一。