Compared to first-and second-generation adenovirus vectors, the third-generation adenovirus vectors have unique advantages for gene therapy because of their low immunogenicity and high capacity.

• 第一、二代腺病毒载体仍有许多不足之处，在其基础上发展了第三代腺病毒载体。第三代腺病毒载体与前者相比，具有低免疫原性及高容量等优点，在基因治疗中表现出独特优势。