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- Recent studies have shown that memory T cells could be divided into central memory T cells and effector memory T cells, which were different in distribution, function and biological characteristics. 近年来的研究表明,记忆性T细胞可以被进一步划分为中枢记忆性T细胞和外周记忆性T细胞2个亚群,它们的分布和功能迥异,在生物学特性上也不尽相同。
- Central memory T cell 中心记忆T细胞
- In the case of active SLE,CCR7+ central memory T c ells may interact with dendritic cells,and induce differentiation of syngeneic CD4+T to Th2 cells. 活动期SLE患者外周血CCR7+中央型记忆性T细胞可与树突细胞相互作用,诱导同系CD4+T细胞向Th2分化,发挥CCR7-CD45RO+效应性记忆性T细胞的功能。
- Seder RA, Ahmed R. Similarities and differences in CD4+ and CD8+ effector and memory T cell generation[J]. Nat Immunol Rev, 2003, 4(9): 835-842. 正常人周围血初始和记忆T细胞亚群及细胞因子表达的探讨由800论文网收集整理,转载请注明出处!
- Background/Aims: To study the expression of CD. ,RA and CD45RO in normal gastric mucosa and gastric cancer, and evaluate the relationship between memory T cell count and TNM staging in gastric cancer. 目的:研究CD45RA、CD45RO在正常胃粘膜及胃癌中的表达,探讨记忆T细胞与胃癌TNM分期的关系。
- ICOS is not expressed on the cell surface of circulating CD8 memory T cells but is rapidly upregulated during cell division within the allograft parenchyma. 在循环CD8记忆T细胞的表明并没有ICOS的表达,但是其在移植物实质内细胞分化期间对其有正性调节作用。
- Recently,it was found that CD127 play an important role as the specific marker of memory T cells and regulator T cells. 近期,随着对CD127研究的不断深入,发现CD127在作为记忆性T细胞及调节性T细胞特异性的表面标记物方面也发挥着重要作用。
- Here, we have tested the role of ICOS co-stimulation in eliciting effector function from these memory T cells. 我们检测了在引出这些记忆T细胞效应器功能中ICOS共刺激通路的作用。
- Although most APCs can present antigen to and activate memory T cells, DCs almost exclusively initiate primary immune responses involving naive T cells. 前列腺干细胞抗原(prostate stem cell antigen,PSCA)是一个新近发现的肿瘤相关性细胞表面抗原,具有前列腺癌特异性。
- Even in the absence of known sensitizing exposures, heterologous immunity and homeostatic T-cell proliferation generate 'endogenous' memory T cells with donor-reactivity. 甚至在不存在明确致敏状况的情况下,一种免疫以及自身内环境稳定的T细胞增殖产生的“内源性”记忆T细胞存在供者反应性。
- Estimates based on the life span of memory T cells suggest it would take in excess of five decades for the reservoir of cells infected with latent HIV to naturally die out. 以记忆T细胞的寿命来估计,有HIV潜伏的细胞需要50年以上才会慢慢自然消失。
- Memory T cell infiltration and ICAM-1 expression in atopic dermatitis 异位性皮炎的记忆性T细胞浸润及ICAM-1表达
- The Relationship between Memory T Cell Count and TNM Staging in Gastric Cancer 胃癌组织中记忆T细胞与TNM分期关系的研究
- The association between memory T cell and co-stimulatory molecule ICAM-1 in the gastric carcinoma with TNM stage 记忆T细胞及粘附分子的表达与胃癌TNM分期关系的研究
- T cell whether synthesize and secrete lymphatic factor? 细胞能否合成和分泌淋巴因子?
- Methods T cell clones were isolated by limiting dilution. 方法通过有限稀释法建立T细胞克隆。
- The computer stops. There's an error, and the central memory has picked it up; it cancels everything. There are no innocents to be saved, in this story. Start again. 计算机停了。报错,中央内存收到信息,一切都取消了。这个故事里没有等待拯救的无辜者。重头再来。
- The first model is based on the expression of CCR7 defined two subsets of memory cells: central memory OCM) and effector memory cells (TEw)- Champagne et al. TcM表达CCR7,缺乏迅速反应的效应功能,但能对细胞因子或病原进行快速的反应并成熟为TEM,失去CCR7的表达,获得组织归巢受体,并大量分泌细胞因子。
- During the inflammation or injury of central nervous syetem (CNS), T cell responses to the CNS antigen,which are initiated by peripheral immune system, act on CNS . 在中枢神经系统 (CNS)炎症或损伤时 ,T细胞对CNS抗原的应答启动于外周免疫系统 ,而作用于CNS。
- Because of this central role in T cell activation, there is a great deal of interest in using DCs therapeutically to diliver positive or negative signals to immune system. 由于DC在T细胞活化中的中心作用,在治疗学上利用DC对免疫系统递送阳性和阴性信号引发广泛兴趣。
