CONCLUSION Hyperoxia can induce acute lung injury and intrinsic Glu release in lungs of newborn rats, which show that Glu may play an important role in hyperoxia-induced lung injury.

• 结论 高浓度氧可引起新生大鼠急性肺损伤，诱导肺组织内源性谷氨酸的释放，提示谷氨酸在高氧性肺损伤中发挥重要作用。