As SV40 plasmids replicate out of control in COS7 cells and be lethal to such transfected cells, SV40 vector/COS7 cell system has only been using as transient expression system for a long time.

• 基于猴病毒40(SV40)载体在COS7细胞内的复制没有节制并对细胞具有致死性,长期以来SV40载体-COS7系统只被用作瞬时表达。