Appearance of withdrawal reactions may associated with pharmacological effects on serotonin, dopamine, norepinephrine, GABA and cholinergic transmitter in central nervous system.

• 撤药反应的出现可能与药物对中枢神经系统中血清素、多巴胺、去甲肾上腺素、GABA、胆碱能类递质系统的影响有关。