After co-cultured with corneal stromal fibroblasts for one week,MSC expressed K12,indicating that they had been transdifferentiated into corneal epithelial cells.

• MSC与角膜基质细胞共培养1wk后大部分细胞分化为间质细胞,少部分细胞形态上相对偏小,免疫荧光检测这部分细胞表达角膜上皮细胞特异性标志角蛋白K12。