Ach-CaCl2 induces myocardial apoptosis. The rule inhibits apoptosis and myocardial fibrosis ,protecting the ultrastructure and decrease the motality.

• Ach-CaCl_2诱导AF小鼠心肌细胞凋亡,温阳益心安神法能够明显抑制心肌细胞凋亡,保护心脏超微结构,在病理形态学方面优势显著,降低AF小鼠死亡率。