8266, a chimeric infectious molecular clone (pOKVltr) was constructed by replaced the long terminal repeat (LTR) sequence of DLA-EIAV with the counterpart of L-EIAV. and its derived virus was generated (designated as vOKVltr).

• 本研究对vOK8226、vOKVltr和DLA-EIAV进行了动物接种试验，通过对临床和病理组织学变化、各结构蛋白抗体、感染马体内病毒载量的监测以及LTR及env基因在感染马体内的变异规律进行了研究。