~(18)F-fluromethylcholine(~(18)F-FCH) as a PET tracer is synthesized. The semi-automatic synthesis assembly of ~(18)F-FCH is modified from CPCU(CTI). The radiochemical purity is measured by analytical HPLC.

• 利用18F-FDG化学合成模块(CPCU)改装的半自动化多用氟标药物仪合成了氟甲基胆碱(18F-FCH),并进行了放射化学纯度测定、稳定性分析、生物分布、荷瘤小鼠显像以及安全性检验。