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- We assessed the effects of annual infusions of zoledronic acid on fracture risk during a 3-year period. 我们评估了在3年周期中，每年注射一次唑来膦酸对骨折风险的影响。
- In this article,we reviewed the progress of zoledronic acid in treating cancer bone metastases. 本文综述了唑来膦酸治疗恶性肿瘤骨转移的研究进展。
- The pharmacological action,pharmacokinetics and clinical research of zoledronic acid are reviewe... 现综述唑来膦酸的药理作用、药动学和临床评价。
- Importantly, the need for mastectomy was reduced by 16 percent in the zoledronic acid group. 更重要的是，添加唑来膦酸治疗组的乳房切除术的需要下降了16%25。
- Neville-Webbe HL,Coleman RE.The use of zoledronic acid in the management of metaststic bone disease and hypercalcaemia[J].Palliat Med,2003,17(6):539. 周锡建;范晓强;李相勇;等.;国产唑来膦酸注射液治疗转移性骨肿瘤[J]
- The effective rate of acesodyne effect in Bonefos , Zoledronic Acid group were 61.54%,80.77% respectively ,showing a significant difference (p<0.05). 控制骨痛有效率;固令组61.;54%25;唑来膦酸组80
- CONCLUSIONS. At 12 months, immediate zoledronic acid therapy prevented bone loss in postmenopausal women who were receiving adjuvant letrozole. 结论：在12个月，接受来曲唑辅助治疗的绝经后患者立即给予唑来膦酸治疗可以防止骨丢失。
- In the trial, 104 patients in the neoadjuvant subset received chemotherapy, and 101 patients received chemotherapy plus zoledronic acid. 试验中，104名患者接受了新的化疗疗法，101名患者接受化疗辅助于唑来膦酸治疗。
- Does Exercise Modify the Effects of Zoledronic Acid on Bone Mass, Microarchitecture, Biomechanics, and Turnover in Ovariectomized Rats? 运动改变唑来膦酸对卵巢切除小鼠骨量、微结构、生物力学和骨转换的作用吗？
- Aromatase inhibitors are superior to tamoxifen in postmenopausal patients, and preclinical data suggest that zoledronic acid has antitumor properties. 芳香酶抑制剂在绝经后患者中优于他莫昔芬，且临床前数据表明唑来膦酸具有抗肿瘤特性。
- The present study assessed the cost effectiveness of zoledronic acid in this population, adopting a UK health care payer perspective. 目前研究评定唑来膦酸有成本效率，已通过英国保健机构的认可。
- Common bisphosphonate medications include alendronate (Fosamax(R)), ibandronate (Boniva(R)), risedonate (Actone(R)) and zoledronic acid (Reclast(R)). 常用的二膦酸盐化合物类治疗药物包括阿伦膦酸盐，伊班膦酸盐，利赛膦酸盐以及唑来膦酸。
- Conclusions The addition of zoledronic acid to adjuvant endocrine therapy improves disease-free survival in premenopausal patients with estrogen-responsive early breast cancer. 结论：联合唑来膦酸的辅助性激素治疗提高绝经前雌激素敏感早期乳腺癌患者的无病存活率。
- Zoledronic acid has recently been shown to significantly reduce the risk of new skeletal related events (SREs) in patients with bone metastases secondary to RCC. 唑来膦酸最近已被证明能减少新的骨骼相关事件的危险对于住院的肾癌继发骨转移病人。
- This analysis was based on a retrospective analysis of a multicenter, randomized, placebo-controlled study of zoledronic acid in 46 RCC patients with bone metastases. 该分析是基于一个46个有骨转移肾癌病人的多中心，随机，安慰剂对照，回顾性研究。
- The drugs, called alendronate and zoledronic acid, are taken to build bone density and as well as to slow down the progression of osteoporosis, which affects more than 3million people in Britain. 阿屈膦酸盐和唑来磷酸这类药物，除能减缓骨质疏松外，还用来增强骨密度，英国有300万人患有骨质疏松。
- Earlier this year, researchers reported phase III Austrian Breast &Colorectal Cancer Study that zoledronic acid added to endocrine therapy improves survival in premenopausal breast cancer patients. 今年早些时候，研究者们报道奥地利的乳腺癌和结肠癌三期患者研究表明，内分泌治疗辅助唑来膦酸治疗可以提高绝经前乳腺癌患者的存活率。
- Keywords zoledronic acid;hypercalcemia;synthesis; 唑来膦酸;高血钙症;合成;
- An improved synthesis of zoledronic acid as a new treating hypercalcemia drug 高血钙症治疗药唑来膦酸的合成方法改进
- Keywords zoledronic acid;radiotherapy;fraction module;osseous metastasis;pain; 唑来膦酸;放射治疗;分割模式;骨转移癌;疼痛;
