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- Total 9 VL,4VK and 7VH chains of variable region genes were obtained. 经PCR方法扩增出了7条VH、9条VL和4条VK片断,经测序证实扩增片断全部为抗体可变区基因。
- The size of the variable region of AMA|1 gene from FCC1/HN was 506 bp and encoded 168 amino acids. FCC1/ HN AMA- 1基因变异区 DNA序列长度为 5 0 6 bp,预计编码 16 8个氨基酸。
- Objective: To acquire the variable region gene of light chain of monoclonal antibodyagainst human retinoblastoma. 目的:获得抗人视网膜母细胞瘤单克隆抗体轻链可变区基因。
- The light chain variable region (VL) gene of the mAb was cloned to pHEN2-VH by the same ways and than the recombinant plasmids were transformed into E. 采用同样的方法将轻链可变区(light chain variable region ; VL)基因克隆至pHEN2-VH,并转化E.
- The 3'NCR of hepatitis C virus (HCV) genome is composed of variable region (VR), polypyrimidine tract (PolyU/UC tract) and X region. 丙型肝炎病毒(Hepatitis C virus,HCV)基因组的3'端非编码区(3' non-coding region, 3'NCR)由可变区(variable region, VR)、多聚嘧啶区(polypyrimidine tract, PolyU/UC tract)和98个核苷酸保守区(X region)组成。
- Methods:PCRs amplifying intI gene and the variable region between the conserved segments (CS-PCR) were performed for class 1, class 2, and class 3 integron. 方法PCR检测细菌总DNA中1、2、3类整合酶基因,确定细菌携带整合子的情况。
- Objective Test the cytokines secretion by peripheral blood mononuclear cells (PBMC) from hepatitis C patients after stimulation with highly variable region (HVR1) synthetic peptides. 目的检测丙型肝炎病毒(HCV)高变区1(HVR1)模拟表位刺激自然感染患者外周血淋巴细胞后的细胞因子水平变化。
- The epitope inducing neutralizing antibody in high variable region 1 (HVR1) is the reason for escape of host immune surveillance, evolution of chronic infection, and also difficulty of producing wide spectrum vaccine. 由于诱导中和抗体的抗原表位恰好位于其包膜抗原E2蛋白的高变区 1(HVR1) ,因而容易逃避机体的免疫监视 ,形成慢性感染 ,同时造成发展广谱预防性疫苗的困难。
- After mice were immunized with BoNTB/Hc, the spleens were harvested ,and single-chain Fv (scFv) and Fab phage antibody libraries were constructed from the immunoglobulin heavy and light chain variable region genes. 用重组表达并纯化的BoNTB/Hc免疫小鼠;从其脾淋巴细胞中提取全套抗体可变区基因;分别构建scFv和Fab段噬菌体抗体文库;库容分别为6.;72x10~7cfu和5
- The heavy chains variable region gene (VH) of monoclonal antibody against beet necrotic yellow vein virus (BNYVV) was amplified from total DNA extracted from anti-BNYVV hybridoma cells by PCR. 用PCR方法以分泌抗甜菜坏死黄脉病毒(BNYVV)单克隆抗体的杂交瘤细胞的基因组为模板,扩增了编码BNYVV单抗的重链可变区(VH)基因。
- Henan Province, situated in a special tectonic and geographic location, abounds in karst resources and bears variable regional characters. 摘要河南处于特殊的大地构造位置和地理位置,岩溶资源丰富并呈现区域性特征。
- Phylogenetic reconstruction with the Neighbor-joining (NJ) method using sequences of variable regions (V1+V2+V3) of SSU rDNA indicated that GYN-15, S. californium and G. 以 SSU r DNA序列中的 3个可变区 (V1 +V2 +V3)和邻接法构建的系统树表明 ;GYN- 1 5与 S.;californium和 G
- RESULTS The similarity in binding activity was found in a group of antibodies which have the analogous paratope specificity and sequences of variable regions... 结合特异性相似的抗体其配位特异性相似,而且可变区序列也相似。[结论]抗体可变区分子结构的相似性决定了抗体结合特异性和配位特异性的一致性。
- METHODS The paratope mapping of antibodies was determined by competitive inhibition in radioimmunoassay and the sequences of variable regions among the antibodies were compared. 应用放射免疫竞争抑制试验测定抗体的配位特异性,并对抗体的可变区序列进行比较。
- OBJECTIVE To map the paratope specificity of autoantibodies in myasthenia gravis and to investigate the correlation between it and the molecular structure of variable regions. 探讨重症肌无力自身抗体配位特异性及其与可变区分子结构的关系。
- Variable region of the light chain, VL 和轻链可变区
- A constant, variable, function name, or expression. 一种常数、变量、函数名或表达式。
- Most insect do not live in polar region. 大多数的昆虫不在极地地区生存。
- The earthquake may cause a region to fall in. 地震可以使一个地区下陷。
- Fuzzy control with variable region 变论域模糊控制