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- Instead, HRASG12V-driven senescence was mediated by the ER-associated unfolded protein response (UPR). 相反,HRASG12V驱动的细胞衰老是由内质网相关未折叠蛋白质应答(UPR)所控制的。
- They show that when a fat cell receives too many nutrients, the ER is overwhelmed and triggers a process called the unfolded protein response (UPR). 他们指出,当脂肪细胞吸收了过多的营养物时,ER就会过载,并会触发一种名为未折叠蛋白质反应(UPR)的过程。
- The disorder of calcium iron and accumulation of unfolded protein can lead to ER stress and thus protective unfolded protein response ensure. 内质网中钙离子紊乱和未折叠蛋白质蓄积,可引发内质网应激,发生具有保护作用的未折叠蛋白反应。
- Unfold protein response in the pathogenesis of ankylosing spondylitis 未折叠蛋白应答在强直性脊柱炎发病机制中的意义探讨
- The disorder of calcium ion and the accumulation of unfolded protein can lead to ER stress and thus induce a protective response-unfolded protein response (UPR). 内质网中钙离子紊乱和未折叠蛋白质蓄积可引发内质网应激(endoplasmic reticulum stress, ERS),发生具有保护作用的未折叠蛋白反应(unfolded protein response, UPR)。
- X-box binding protein 1 (XBP1), as a transcription factor of unfolded protein response (UPR), is found to be closely related with protein folding in endoplasmic reticulum (ER). 研究发现X-盒结合蛋白1(X-box binding protein1,XBP1)与内质网中蛋白质的折叠密切相关,参与调控未折叠蛋白的折叠、修饰、分选与包装;
- We report here that glucose-regulated protein(GRP)-78, a critical regulator of the unfolded protein response (UPR), is a novel downstream target of BRCA1. 我们的报告在这里葡萄糖调节蛋白(玻璃钢) -78 ,一个关键调节器的折叠蛋白反应(不饱和聚酯树脂) ,是一种新型的下游目标, BRCA1基因。
- GRP94 is a stress protein whose transcriptional level increases under several physiologial and pathological conditions. This is the unfolded protein response ( UPR) pathway which associates with the signal transferring from ERs to nucle-us. GRP94作为应激蛋白,其转录水平在许多生理和病理条件下都可明显升高,与此相关的从内质网到细胞核的信号传导通路就是未折叠蛋白反应(the unfolded protein response,UPR)通路。
- Cells respond to the accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) by up-regulating ER-resident enzymes at the transcription level. This is referred to the unfolded protein response (UPR). 未折叠或错误折叠的蛋白质在内质网(endoplasmic reticulum,ER)中聚集促使细胞做出适应性反应,包括上调位于内质网的各种酶和分子伴侣,这被称为未折叠蛋白反应(unfolded protein response,UPR)。
- unfold protein response 未折叠蛋白反应
- The Relationship between Unfolded Protein Response and Diseases 未折叠蛋白应答与疾病的关系
- Keywords Hepatitis C virus (HCV);NS4B;Unfolded protein response (UPR); 丙型肝炎病毒;非结构蛋白质4B;非折叠蛋白反应(UPR);
- Regulation mechanism of unfolded protein response: progress and clinical prospect 未折叠蛋白应答通路调控机制的研究进展及其临床应用前景
- UNFOLDED PROTEIN RESPONSE IS INVOLVED IN THE DIFFERENTIATION OF EMBRYONIC STEM CELLS INDUCED BY RETINOIC ACID 未折叠蛋白反应对维甲酸诱导鼠胚胎干细胞分化的作用
- The Effects of the Unfolded Protein Response (UPR) in ER on Cell Adesion and Migration in HEK293 Cells in Vitro 非折叠蛋白质应答对HEK293细胞迁移与粘附的影响
- Keywords endoplasmic reticulum stress;unfolded protein response;integrated stress response;endoplasmic reticulum associated death; 内质网应激;未折叠蛋白反应;整合应激反应;内质网相关性死亡;
- Keywords Embryonic stem cell;All trans retinoic acid;Cell differentiation;Unfolded protein response;Endoplasmic reticulum; 胚胎干细胞;全反式维甲酸;细胞分化;未折叠蛋白反应;内质网;
- Keywords Endoplasmic reticulum;glucose-regulated proteins;unfolded protein response;molecular chaperone; 内质网;葡萄糖调节蛋白;未折叠蛋白反应;分子伴侣;
- unfolded protein response (UPR) 未折叠蛋白应答
- Unfolded protein response 未折叠蛋白反应