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- Treatment with two oligonucleotides directed against the coding region and the translation initiation region of bcl 2 messenger RNA/VP 16 combination respectively for 48 h had significantly reduced the number of viable AL cells. 靶向 bcl- 2 m RNA翻译起始区与靶向蛋白编码区的两个反义寡核苷酸分别与 VP1 6 联合作用 AL 细胞 4 8h;细胞的生存受到明显的抑制 ;分别同无关寡核苷酸 (NS- ODN)联合 VP1 6 组、单用 VP1 6 组进行比较 ;差异有显著性 (P<0 .;0 5 )。
- There is a secondary struct ure complex at the translation initiation region of apr mRNA.When one of the se condary structure complex at the translation initiation region of apr mRNA. 依赖链霉素突变在翻译层次抑制碱性蛋白酶基因的表达,但对中性蛋白酶基因的表达没有影响。
- Effects of Translation Initiation Region Secondary Structure on Expression of Luciferase Gene in COS-7 Cells 翻译起始区二级结构对荧光素酶基因在COS-7细胞中表达效率的影响
- Keywords translation initiation region;luciferase;secondary structure;expression; 翻译起始区;荧光素酶;二级结构;表达;
- translation initiation region 翻译起始位点
- AUG depletion may be an indication that upstream AUG can probably disturb the translation initiation of bacteria and archaea. AUG的缺失表明在起始密码子上游的AUG很可能会对基因的翻译起始产生影响。
- The sequences and secondary structures of IRES are compared.Interaction between IRES and translation initiation factors and relation with virulence of FMDV is summarized. 本文对IRES的一、二级结构进行了比较,对IRES与翻译起始因子的相互作用以及对病毒毒力的影响作了综述。
- A vitamin D receptor gene polymorphism in the translation initiation codon: effect on prote in activity and relation to bone mineral density in Japanese women. 更难理解的是为什么这些等位基因有时存在,有时不存在,有时甚至是相反的结果。
- Based on the position weight matrix(PWM) and length distribution of open reading frame(ORF),a simple method for predicting translation initiation sites is presented. It can identify TIS from upstream AUGs easily. 结合位置权重矩阵(PWM;position weight matrix)和开放阅读框架(ORF;open reading frame)的长度分布特征建立了简单的方法识别翻译起始位点;此方法能很好地区分上游AUG和TIS.
- Methods The DNA fregment target to the translation initiation site of CCR5 mRNA obtained by RT - PCR from peripheral blood mononuclear cells(PBMCs)was cloned into retro-viral vector pLXSN. 方法 用RT-PCR从健康人外周血单个核细胞(PBMCs)中获得趋化因子受体CCR5翻译起始区的基基片段,用基因重组技术将此目的基因以正、反两个方向定向插入到逆转录病毒载体pLXSN。
- Objective To investigate the effect of a new cloned full length gene, C2 gene which encodes a translation initiation factor, on cell cycle and the relationship between C2gene and apoptosis. 目的探索新克隆的编码人蛋白翻译起始因子的全长基因(C2基因)对细胞周期的影响及与细胞凋亡的关系。
- Methods The ASODNs including the translation initiation site of ATP7B mRNA was artificially synthesized, and the sense oligodeoxynucleotide corresponding to the ASODNs was also synthesized as control. 方法 人工合成包含ATP7B mRNA 翻译起始位点的反义寡核苷酸片段及正义寡核苷酸片段作为对照。
- Factors in the Translation Initiation of FMDV 影响口蹄疫病毒转译起始的因素
- Eukaryotic Translation Initiation Factors and Tumor 真核翻译起始因子与肿瘤
- Second, the initial regions are hierarchically merged based on the region distance defined by the color and spatial information. 中国科学院研究生院网络多媒体研究中心;北京100039 黄铁军%24中国科学院计算技术研究所数字化实验室!
- Eukaryotic translation initiation factor 4E 翻译启动因子4E蛋白
- Eukaryotic translation initiation factor 5A (eIF5A) 真核生物翻译起始因子
- Most insect do not live in polar region. 大多数的昆虫不在极地地区生存。
- Eukaryotic translation initiation factor4E 真核细胞翻译起始因子4E
- The earthquake may cause a region to fall in. 地震可以使一个地区下陷。