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- A vitamin D receptor gene polymorphism in the translation initiation codon: effect on prote in activity and relation to bone mineral density in Japanese women. 更难理解的是为什么这些等位基因有时存在,有时不存在,有时甚至是相反的结果。
- translation initiation codon 翻译起始密码子
- Keywords rice;chloroplast;mitochondrion;codon usage bias;gene function;translation initiation codon;translation termination codon;sequence pattern;gene expression level;readthrough gene; 水稻;叶绿体;线粒体;密码子偏好性;基因功能;起始密码子;终止密码子;侧翼序列模式;基因表达水平;通读基因;
- The initiation codon represents the first amino acid, N-formyl methionine, at the N terminus of the polypeptide. 即编码多肽N-端第一个氨基酸即甲硫氨酸(N-甲酸化的)的密码子。
- AUG depletion may be an indication that upstream AUG can probably disturb the translation initiation of bacteria and archaea. AUG的缺失表明在起始密码子上游的AUG很可能会对基因的翻译起始产生影响。
- A deletion of adenosine (A), at -241 (relative to initiation codon ATG), designated as Del(A) allele, was found in Laiwu compared with Yorkshire (GenBank accession number DQ463321-22). 克隆了猪DGAT1 5’调控区的部分序列(737 bp),在-241bp(相对于起始密码子ATG)发现一处由单个腺嘌呤(A)缺失产生的新SNP位点(定义为等位基因Del(A) ) (GenBank收录号:DQ463321-22);
- The sequences and secondary structures of IRES are compared.Interaction between IRES and translation initiation factors and relation with virulence of FMDV is summarized. 本文对IRES的一、二级结构进行了比较,对IRES与翻译起始因子的相互作用以及对病毒毒力的影响作了综述。
- Based on the position weight matrix(PWM) and length distribution of open reading frame(ORF),a simple method for predicting translation initiation sites is presented. It can identify TIS from upstream AUGs easily. 结合位置权重矩阵(PWM;position weight matrix)和开放阅读框架(ORF;open reading frame)的长度分布特征建立了简单的方法识别翻译起始位点;此方法能很好地区分上游AUG和TIS.
- Methods The DNA fregment target to the translation initiation site of CCR5 mRNA obtained by RT - PCR from peripheral blood mononuclear cells(PBMCs)was cloned into retro-viral vector pLXSN. 方法 用RT-PCR从健康人外周血单个核细胞(PBMCs)中获得趋化因子受体CCR5翻译起始区的基基片段,用基因重组技术将此目的基因以正、反两个方向定向插入到逆转录病毒载体pLXSN。
- Treatment with two oligonucleotides directed against the coding region and the translation initiation region of bcl 2 messenger RNA/VP 16 combination respectively for 48 h had significantly reduced the number of viable AL cells. 靶向 bcl- 2 m RNA翻译起始区与靶向蛋白编码区的两个反义寡核苷酸分别与 VP1 6 联合作用 AL 细胞 4 8h;细胞的生存受到明显的抑制 ;分别同无关寡核苷酸 (NS- ODN)联合 VP1 6 组、单用 VP1 6 组进行比较 ;差异有显著性 (P<0 .;0 5 )。
- Objective To investigate the effect of a new cloned full length gene, C2 gene which encodes a translation initiation factor, on cell cycle and the relationship between C2gene and apoptosis. 目的探索新克隆的编码人蛋白翻译起始因子的全长基因(C2基因)对细胞周期的影响及与细胞凋亡的关系。
- Using the home-made Perl programs, we extracted the concerned bases upstream and downstream of both the initiator codon and the stop codon for analysis. 通过自编的系列Perl程序,从智人RefSeq数据库中分别抽取mRNA序列起始密码子、终止密码子上、下游一定数目碱基进行分析,得出以下主要结论:
- Methods The ASODNs including the translation initiation site of ATP7B mRNA was artificially synthesized, and the sense oligodeoxynucleotide corresponding to the ASODNs was also synthesized as control. 方法 人工合成包含ATP7B mRNA 翻译起始位点的反义寡核苷酸片段及正义寡核苷酸片段作为对照。
- There is a secondary struct ure complex at the translation initiation region of apr mRNA.When one of the se condary structure complex at the translation initiation region of apr mRNA. 依赖链霉素突变在翻译层次抑制碱性蛋白酶基因的表达,但对中性蛋白酶基因的表达没有影响。
- The complete VP1 gene of CVB2 Yunnan strain had a total length of 846bp and without initiator codon and terminator codon. The highest similarity of VP1 gene with Ohio 1 strain(GenBank logging number:AF081312) nucleotide and amino acid sequence was 98% . CVB2云南分离株VP1基因全长约846bp,无起始密码及终止密码,与Ohio-1株(GenBank登录号:AF081312)核苷酸、氨基酸序列同源性最高为98%25。
- Factors in the Translation Initiation of FMDV 影响口蹄疫病毒转译起始的因素
- Eukaryotic Translation Initiation Factors and Tumor 真核翻译起始因子与肿瘤
- Eukaryotic translation initiation factor 4E 翻译启动因子4E蛋白
- Eukaryotic translation initiation factor 5A (eIF5A) 真核生物翻译起始因子
- Eukaryotic translation initiation factor4E 真核细胞翻译起始因子4E