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- Conclusion LPL is a key enzyme in lipid metabolism and LPL gene knockout can influence the levels of lipid in serum and tissue. 结论LPL是脂代谢的关键酶，LPL(+/-)小鼠血清及组织脂质变化显著。
- Abstract: Regulation of specific proteins by phosphorylation is usually overlooked by standard loss-of-function approaches such as RNAi or gene knockout, which simply remove the gene or protein. 摘 要： 常规 R NA 干涉或基因敲除的功能缺失手段仅仅只是简单地移除某个基因或蛋白，而这个过程常常会掩盖磷酸化对某个特定蛋白的调节。
- Transgenic or knockout of specific genes have led to the development of rodent models of spontaneous colitis. 转基因和基因敲除动物模型带动了自发性结肠炎动物模型的发展。
- A full description is given on the structure, the unique tissue specific expression pattern , the factors and mechanisms involved in the expression regulation of the gene of aromatase,CYP19. 综述了编码该酶的CYP19基因的结构、独特的组织特异性表达和调控CYP19基因表达的各种因素及其有关的调控机制。
- Molecular techniques such as gene knockout partially support the monoamine theory of depression. 诸如基因部分敲除的分子技术支持抑郁症的单胺理论。
- We also detected BMD in APN gene knockout mice to evaluate the relationship between adiponectin and bone metabolism. 对骨代谢的初步研究采用检测小鼠骨密度(BMD)的方式。
- Processes involved in the site-specific effect of probucol on atherosclerosis in apolipoprotein E gene knockout mice. (有关普罗布考对载脂蛋白E基因敲除小鼠的动脉粥样硬化的位点专一作用)。
- Therefore, CRES may perform unique and tissue specific functions in the reproductive and neuroendocrine systems. 因此 ,CERS在生殖系统和神经内分泌系统中的功能也许是独特的和组织特异性的。
- tissue plasminogen activator gene knockout mice 组织型纤溶酶原激活剂基因敲除小鼠
- It enables a specific gene to be located on a particular restriction enzyme fragment. 它就能使专一的基因被定位于特定的限制性内切酶切成的片段上。
- In 2002, Anderson, MS reported that Aire could regulate the transcription of many tissue specific antigens in mTECs. 2002年，Anderson，MS等报道了Aire可以调节多种组织特异性抗原在mTECs的转录。
- Conclusion: The results shows that no significant alteration on glycometabolism or bone metabolism was found in APN gene knockout mice. 结论：脂联素基因剔除小鼠在基础状态下并无显著的糖代谢和骨代谢异常。
- The 2.2 kb of the MIA promoter contains cis acting elements which can generate tissue specific expression in vivo . 2.;2 kb 的MIA/CD－RAP启动子含有调节MIA/CD－RAP组织特异性表达的顺式调控元件
- Methods: We detected the weight and glucose level in APN gene knockout mice and evaluated the ability of glycometabolism by GTT and ITT. 方法：采用长期追踪野生型和该基因剔除纯合子小鼠的体重和空腹血糖水平，并进行葡萄糖耐量(GTT)和胰岛素耐量(ITT)试验以评价该小鼠的葡萄糖代谢能力。
- It was clear in RT-PCR that human myocardial specific gene MLC-2V. MLC-2A. a-MHC. CTnT. RT-PCR显示，移植hEBDs的鸡胚心肌中有人心肌特异性的基因MLC-2V、MLC-2A、-MHC、CTnT、ANP与NKx-2.;5等表达。
- It was speculated that the cis acting element in region A might determine the tissue specific expression character of A33 promoter. 推测A区所包含的顺式调控元件很可能是决定A33基因组织特异性表达的关键元件 .
- The locomotion of mtm-5 gene knockout group is obviously faster than control group, this suggests that MTM-5 also plays a negative regulation role in the muscle development. mtm-5基因敲除型线虫的运动能力明显比对照组快，暗示其可能与肌肉系统以及整体的发育存在着某种负调控的联系。
- Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone. 高同型半胱氨酸血症诱导同型半胱氨酸在骨骼中通过与胶原结合的组织特异性沉积，并对骨骼造成不良影响。
- Howeer, uniparental ES cell research faces the biological hurdle of genomic imprinting, in which specific gene expression patterns are dictated by the parental origin. 然而，单系胚胎干细胞研究面临着基因组印迹的生物学障碍，即特殊的基因表达模式受原始亲代的控制。
- This would seem to prevent researchers from making dog "knockouts" lacking a specific gene or engineering dogs that produce mutant forms of a gene. 因为缺少一种特定的基因或能产生突变基因的转基因狗，研究人员可能无法进行狗基因敲除。
