the incidence of ADR was 6.6%(11/167), and the main clinical manifestations were sickness, vomiting, diarrhea, numbness of mouth and lip, fever, and mycoinfection.

• 不良反应发生率6·6%25(11/167),主要表现为恶心、呕吐、腹泻、口唇麻木、发热、霉菌感染等。