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- Keywords taxol;taxane xyloside;Taxus extracts;selective oxidation-hydrolysis; 紫杉醇;糖基化紫杉烷;红豆杉浸膏;选择性氧化水解;
- taxane xyloside 糖基化紫杉烷
- The other taxane, Taxotere (docetaxel) is more potent than Taxol. 另一紫杉烷,紫杉特尔(紫杉萜)比紫杉酚更有效。
- AIM Taxane diterpenoid compounds are expected to be isolated from Taxus chinensis cell cultures. 目的:从中国红豆杉细胞培养物提取紫杉烷类二萜化合物。
- The researchers also observed high rates of probable clinical depression among patients who received taxane therapy. 研究还发现这些患者更容易出现临床抑郁症状。
- Nowaday, The chemotherapeutic drugs of anthracycline and taxane are used widely in breast cancer. 目前乳腺癌辅助化疗应用最多的仍是蒽环类及紫杉类药物。
- The Phase III data on Adriamycin taxane combinations are more mature than those exploring the value of Epiadriamycin. 对阿霉素+紫杉类的III期临床数据要比研究表阿霉素联合化疗更加成熟。
- It was proved that taxane alone can get more benefit than anthracycline alone in breast cancer. 已证明,单用紫杉类比单用蒽环类药物疗效更好。由于具有不同的抗癌机制,紫杉类与蒽环类联用可取得更好疗效。
- BacgroundDocetaxel is a semisynthetic taxane that affects polymerized tubulin both topromote microtubule formation and to inhibit its disassembly. 研究背景:多烯紫杉醇是一种半化学合成的紫杉醇,它可促进微管聚集,稳定微管结构,阻止微管解聚。
- In this paper, the semisynthesis of taxol and various synthetic methods for construction ofthe taxane ring are reviewed. 本文对紫杉醇的半合成和紫杉烷环的各种合成方法进行了综述。
- Purpose: An anthracycline-based combination followed by, or combined with, a taxane is the sequence used in most adjuvant chemotherapy regimens. 目的:以蒽环类抗生素为基础序贯或联合紫杉烷是在很多的辅助化疗方案里的顺序。
- Stierle A , Strobel G , Stierle D .Taxol and Taxane Production by Taxomyces andreanae, An Endophytic Fungus of Pacific Yew. Science,260:214. 郭波;李海燕;张玲琪.;一种产长春碱真菌的分离
- One important feature of anthracycline+ taxane combinations is the higher risk of febrile neutropenia than is seen with single-agent therapy and with Adriamycin+ Cytoxan. 蒽环类与紫杉类联合的一个重要特点是与单药治疗和阿霉素+磷酰胺相比,发生发热性中性粒细胞减少的危险增高。
- One important feature of anthracycline + taxane combinations is the higher risk of febrile neutropenia than is seen with single-agent therapy and with Adriamycin + Cytoxan. 蒽环类与紫杉类联合的一个重要特点是与单药治疗和阿霉素+环磷酰胺相比,发生发热性中性粒细胞减少的危险增高。
- One important feature of anthracycline taxane combinations is the higher risk of febrile neutropenia than is seen with single-agent therapy and with Adriamycin Cytoxan. 蒽环类与紫杉类联合的一个重要特点是与单药治疗和阿霉素+环磷酰胺相比,发生发热性中性粒细胞减少的危险增高。
- Their psychologic recovery was significantly slower, requiring an average of 2 years, compared with the 6 to 12 months required by patients who did not receive taxane. 她们的情感恢复明显缓慢,平均需要2年,而未接受紫杉烷类治疗的患者仅需半年到一年。
- We hypothesized that administering the taxane before the anthracycline combination would be associated with fewer dose reductions and delays than the reverse sequence. 我们假设联合方案中在蒽环类抗生素之前给紫杉烷与相反的顺序相比可以有更少的剂量减少和阻滞。
- The researchers also observed that patients who received taxane agents had significantly worse emotional distress and mental quality of life throughout the treatment period. 研究还发现接受紫杉烷类治疗的患者在整个治疗期间均更容易出现情绪低落、情感生活治疗下降。
- And it suggested the possibility to exploit the new approch for isolation taxol and taxane derivatives from yew - microbes symbiotic system and from the genus Taxus. 提出从红豆杉-微生物共生系统、红豆杉近缘科属植物中筛选发掘紫杉醇及同系物的新途径的可能性。
- Of the 7 choices provided I would choose either a taxane or gemcitabine with a platinum compound as optimal therapy at this point in time (Choice 1, 2 or 4). 在这7个选项中,我选择紫杉类或健择与铂类联合作为最佳治疗(选项1,2或4)。