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- Objective To identify nasal polyp susceptibility gene locus by genome-widp scan for familial nasal polyps. 目的对鼻息肉家系进行全基因组扫描,从而找出鼻息肉易感基因的位点。
- Hox gene family?s A,B, D clusters ma y be susceptibility genes of CDH. 先天性髋脱位与Hox基因A ,B和D簇可能有关联 ,HoxA ,B和D簇基因可能是先天性髋脱位的易感基因
- God is not unfair, but because he and his wife are born with lung cancer susceptibility gene there. 不是上帝不公平,而是因为他老婆与俱生下来就有肺癌易感基因。
- Abnormality of breast cancer susceptibility gene (BRCA) is of great significance, especially in the development of breast cancer. 乳腺癌易感基因,尤其是BRCA的异常在乳腺癌发病中更具意义。
- It has been identified that filaggrin gene is a susceptibility gene for AD, and the defect and loss of filaggrin protein may be a major cause of xerotic skin diseases. 中间丝蛋白基因突变是特应性皮炎发病的重要易患因素之一,中间丝蛋白的减少和缺失, 可能是引起特应性皮炎等干燥性皮肤病的主要原因。
- Objective To detect the expression of the tumor susceptibility gene TSG101 in sarcoma to investigate the potential role of TSG101 in the pathogenesis of sarcoma. 目的检测肿瘤易感基因TSG101在肉瘤的表达情况,探讨其表达在肉瘤发生中的可能作用。
- The study showed that HLA-DR6 gene might be one of the susceptibility genes to ICP. ICP患者HLA DR6基因可能是ICP发病的易感基因之一。
- PAX5 and PAX6 genes may have nothing to do with CCF while TBX3 gene may be the susceptibility gene for CCF. 先天性马蹄内翻足可能与PAX5、PAX6基因无关联,TBX3基因可能是先天性马蹄内翻足的易感基因。
- Conclusions PAX5 and PAX6 genes may have nothing to do with CCF while TBX3 gene may be the susceptibility gene for CCF. 结论先天性马蹄内翻足可能与PAX5、PAX6基因无关联,TBX3基因可能是先天性马蹄内翻足的易感基因。
- CDH is associated with the region of chromosome 17q21. HOXB9 gene and/or COL1AI gene may be susceptibility genes of CDH. CDH与 HOXB9基因和 COL1A1基因共同所在的染色体区域 17q2 1有关联 ,HOXB9基因和 (或 ) COL1A1基因可能是 CDH的易感基因
- Objective: To investigate the expression of breast cancer susceptibility gene 2(BRCA2) in sporadic breast cancer tissue and its significance,and to clarify the correlation of the expression of the BRCA2 protein with the expression of C-erbB-2,ER and PR. 目的:探讨乳腺癌易感基因2(BRCA2)在散发性乳腺癌组织中的表达及意义,了解BRCA2蛋白的表达与雌激素受体(ER)、孕激素受体(PR)及原癌基因C-erbB-2之间的相关性。
- DMA*0101 and DMB*0101 alleles may be the susceptibility genes or closely linked to the susceptibility gene in Cantonese patients with CA. HLADMA*0101和DMB*0101等位基因可能是汉族人CA的易感基因或与易感基因连锁。
- Tools emerging from the human genome project hae enabled the identification of these susceptibility genes. 自从人类遗传组学出现以后,已经有办法鉴别那些易患基因。
- Reports of one of its susceptibility genes, ethyltracatechol-O-mnsferase (COMT) have been conflicting. 对其易感基因,儿茶酚氧位甲基转移酶基因(COMT)的众多报道充满了矛盾。
- Now candidate gene analysis and whole genome screening have been used to identify the susceptibility genes and loci contributing to the etiology of AITD. 目前已利用候选基因筛查和全基因组扫描的方法来识别AITD的易感基因和位点。
- Quite a few kinds of genes such as susceptibility gene,oncogene and tumor suppressor genes have been found with implications for diagnosis, therapy and prognosis. 其中涉及多种基因异常,包括易感基因、癌基因、抑癌基因等,对于乳腺癌的诊断、治疗及预后判断均具有提示作用。
- Studies have shown that the susceptibility genes of intracranial aneurysm play a very important role in its pathogenesis. 研究表明,颅内动脉瘤的易感基因在其发病机制中起着非常重要的作用。
- By analyzing altofrequent chromosome mutations, CGH can provide locating information for screening susceptibility genes of cutaneous tumors. 用比较基因组杂交分析皮肤肿瘤高频率的染色体变异,将为相应肿瘤易感基因的筛选提供定位资料。
- Efforts to identify susceptibility genes do not generally take into account possible interaction with environment, life experience and psychological characteristics. 易感基因鉴别工作一般没有考虑与环境、生活经历、心理特征的可能相互作用。
- One of the earliest benefits of the identification of susceptibility genes is that the validity of current nosological categories can be further explored. 最早的鉴别易感基因的好处之一就是对现行的疾病分类学的范畴的有效性可以进行更多的探索。