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- Keywords Sumatriptan succinate;Synthesis;Process; 琥珀酸舒马曲坦;合成;工艺;
- sumatriptan succinate 琥珀酸舒马曲坦<抗偏头痛药>
- Chloramphenicol Sodium Succinate for Inj. 注射用琥珀氯霉素钠。
- Methods:10%diethyleneglycol succinate(DEGS) column was chosen. 方法 :选用丁二酸二乙二醇酯 (DEGS)色谱柱。
- Succinate was the most effective substrate in following oxygen consumption. 琥珀酸盐在以后的氧消耗中是最有效的基质。
- Tetradecyl hydrogen succinate(THS) was synthesized by esterification method. 本文合成了软X射线分光晶体琥珀酸氢十四酯(THS)。
- Addition of succinate buffer and Tween 80 facilitated CDH secretion. 培养基中加入琥珀酸钠缓冲液和土温80利于酶的合成。
- The sodium citrate, sodium succinate can enhance the degradation of phenol. 柠檬酸钠、琥珀酸则能促进其对苯酚的降解。
- POZEN Inc and GlaxoSmithKline Inc, the maker of sumatriptan, supported this study and employ 4 of its authors. 作为舒马曲坦的制造公司，Pozen公司和葛兰素史克公司支持了这项研究并且雇用了其中的4名作者。
- For attacks of cluster headache oxygen and subcutaneous sumatriptan can be used. 吸氧和皮下注射舒马普坦被用来治疗丛集性头痛。
- Results and conclusion The structure of sumatriptan was characterized by 1H-NMR, IR and MS. 结果与结论目标化合物的结构经1H-NMR、IR和MS确证。
- Sumatriptan Normalizes the Migraine Attack-Related Increase in Brain Serotonin Synthesis. 偏头痛患者的5-TH浓度有哪些变化？
- As a high-selective 5-HT1D receptor agonist, sumatriptan is mainly used as an emergency medicine in the treatment of migraine and cluster headache. 舒马曲坦为具有高度选择性的5-HT1D受体激动剂,主要用作偏头痛和丛集性头痛发作的急救药。
- The therapeutic gain for headache relief is 50% for subcutaneous sumatriptan whereas it is 30-40% for most oral triptans. 皮下注射舒马普坦有50%25的缓解率，而口服只有30%25到40%25。
- N-Methyl-4-aminobenzyl sulfonamide, a key intermediate for synthesis of the pharmaceutical substance Sumatriptan, was prepared throught four steps. 该合成方法鲜见报道,且操作简单,所得产品纯度也较高,可以用来进一步合成药物舒马普坦。
- Objective To appraise clinical efficacy and safety of national loxapine succinate in schizophrenics. 目的评价国产丁二酸洛沙平对精神分裂症的临床疗效与安全性。
- Ethyl succinyl chloride was synthesized with monoethyl succinate and thionyl chloride as raw materials. 以丁二酸单乙酯和氯化亚砜为原料合成丁二酸单乙酯酰氯。
- Triptans is a kind of important drug for migraine.So far, sumatriptan, nalatriptan,zlmitriptan, zizatriptan, almotritan, eletriptan and frovatriptan have appeared on the market. 曲坦类化合物是一类重要的治疗偏头痛的药物,现已开发出来的有舒马曲坦,纳拉曲坦、佐米曲坦、利扎曲坦、阿莫曲坦、依利曲坦和氟伐曲坦。
- The main varieties, application, development and market prospects of anionic surfactant sulfo succinate are reviewed. 综述了阴离子表面活性剂磺基琥珀酸盐的主要品种，应用和新产品开发，及其广阔的市场前景。
- It has been found that the oxidation of succinate was inhibited by amytal plus isocitrate. 鼠肝线粒体加入Amytal与异柠檬酸或柠檬酸后琥珀酸的氧化即受到抑制。
