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- To explore the improved preparation of protoporphyrin disodium, observe the cytotoxicity of Napp in vitro and its inhibitory effect on HCV subgenomic replicon cell model. 目的本研究对原卟啉钠的制备方法进行了改进,以期简化其生产流程。
- Keywords Napp;HCV;inhibit;HCV subgenomic replicon; 原卟啉钠;丙型肝炎病毒;抑制;HCV亚基因复制子细胞;
- Construction and Application of Subgenomic Replicon Vectors of Japanese Encephalitis Virus 日本脑炎病毒(JEV)复制子表达载体的构建及其鉴定
- This T-cell/HCV subgenomic replicon system represents a model for the investigation of CD8 cell interaction with HCV-infected hepatocytes. (HEPATOLOGY 2003; 这个T细胞/HCV亚基因组复制子系统代表了对于CD8细胞和HCV感染的肝细胞之间相互作用研究的一种模型。
- subgenomic replicons 亚基因复制子
- Each segment of DNA thus synthesized is called a replicon. 这样合成的每一片段DNA称为复制子。
- Newly-synthesized DNA strands from adjacent replicons are ligated together. 来自邻近的复制子的新合成的DNA链又连结在一起。
- Whether the presence of HBV subgenomic fragments in PBMC can affect cell function should be pursued. HBV亚基因片段在PBMC中，是否会影响细胞的功能，有待进一步研究。
- This result was also confirmed by neomycin gene-containing replicons with same mutations. 这一结果在新霉素包含子转染中也得到了证实。
- He was one of the first to show that drug resistance genes could move from one replicon to another in bacteria. 他首次指出在细菌中抗药基因可以从一个复制子转移到另一个。
- This study as well as others have also shown an antiviral effect of cyclosporine in HCV replicon models [37，38]. 这项研究，包括其它一些研究都表明环孢菌素对丙肝复制模型有抗病毒作用[37，38]。
- HCV replicon cells express homozygous HLA-A11 alleles and present HCV nonstructural proteins. HCV复制子细胞表达纯合子HLA-A11等位基因并呈递给HCV非结构蛋白。
- Azathioprine has also been shown to have an anti-HCV effect in the replicon model [39]. 同样，咪唑硫嘌呤也显示出抗病毒作用[39]。
- Both the constructed plasmids pSMLFPGA and pKKFPGA contained the PGA gene ,trc promoter and rrnB transcript terminator, differ in the replicon and antibotic marker, pKKFPGA contained multicopy replicon(COLE 1) and ampicillin marker . 本文将粪产碱杆菌青霉素G酰化酶(AfPGA)基因构建表达载体pKKFPGA和pSMLFPGA，pKKFPGA和pSMLFPGA均含trc启动子、青霉素G酰化酶基因、rrnB转录终止子，其中pKKFPGA含有氨卞青霉素抗性基因和colE1高拷贝复制子；
- RNA Replicon Vaccine and Packaging System RNA复制子疫苗及其包装系统
- Keywords RNA replicon;vaccine;alphavirus; RNA复制子;疫苗;甲病毒;
- Keywords Hepatitis C Virus;Replicon;Cell model; 肝炎病毒;丙型;复制子;细胞模型;
- Keywords dengue virus;replicon;Renilla luciferase; 登革病毒;复制子;海肾萤光素酶;
- Development and Characterization of SARS-CoV Replicon Cell Line 可复制SARS冠状病毒的细胞系的开发和表征
- Keywords HIV;replicon of SFV;Eukaryotic expression vector;IFA; 塞姆利基森林病毒复制子;真核表达载体;IFA;
- 今日热词
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- 深远海浮式风电平台 - deep-sea floating wind power platform
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- 京雄高速公路 - Beijing-Xiongan expressway
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- 农业及相关产业增加值 - the added value of agriculture and related industries
