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- Using the home-made Perl programs, we extracted the concerned bases upstream and downstream of both the initiator codon and the stop codon for analysis. 通过自编的系列Perl程序,从智人RefSeq数据库中分别抽取mRNA序列起始密码子、终止密码子上、下游一定数目碱基进行分析,得出以下主要结论:
- This fragment three flanking end location is in the first translation start codon ATG (+1) up stream 128 bp. 这段片段的3’端起始点在第一个外显子里第一个翻译密码子ATG(+l)上游128 bp处。
- The first ATG rule for recognizing the start codon of gene coding sequences is given. 提出了一个识别基因起始密码子的第一ATG规则.
- Furthermore, a fragment of 150bp from start codon ATG to 150nt showed the most variation. 从ATG至第150bp区段的核苷酸序列变异频率最高。
- The complete VP1 gene of CVB2 Yunnan strain had a total length of 846bp and without initiator codon and terminator codon. The highest similarity of VP1 gene with Ohio 1 strain(GenBank logging number:AF081312) nucleotide and amino acid sequence was 98% . CVB2云南分离株VP1基因全长约846bp,无起始密码及终止密码,与Ohio-1株(GenBank登录号:AF081312)核苷酸、氨基酸序列同源性最高为98%25。
- The detection rates of pre-S2 start codon mutation were significantly different in different groups: from 50.00% (HCC), 39.47% (LC), 8.00% (CH), to ASC (0). 前S2起始码变异在HCC、LC组的检出率分别为50.;00%25、39
- In human cDNA sequencing projecs, it is vital to know whether the first ATG codon is a real start codon or an in frame Met codon without initiation function. 在人类cDNA序列确定全长基因的过程中 ;必须判断第一个ATG密码子是真正的起始密码子还是框内的非起始作用的甲硫氨酸密码子 .
- DNA sequencing revealed that the IPNS gene of S. cattleya consists of 963 bp encoding a protein of 321 amino acids with ATG as start codon, TGA as stop codon. 经基因序列分析表明牲畜链霉菌中IPNS基因;由963bp组成;起始密码子为ATG;终止密码子为TGA;共编码321个氨基酸;所克隆的牲畜链霉菌IPNS基因编码蛋白与已知的S.
- The detected ratios of pre-S2 start codon and pre-S deletion mutations were significantly higher in genotype C than in genotype B (43.04% vs 1.23%, 36.71% vs 19.75%, P < 0.05, respectively). C基因型前S2起始码变异的检出率为43.;04%25;高于B型的1
- The distance and the composition between the Shine-Dalgarno(SD)sequence and the start codon have, profound effect on the expression of prochymosin gene causing a 15fold difference. Shine-Dalgarno序列与起始密码子之间的距离与组成对凝乳酸原基因表达有明显的影响,可导致其表达水平有15倍之差。
- The initiation codon represents the first amino acid, N-formyl methionine, at the N terminus of the polypeptide. 即编码多肽N-端第一个氨基酸即甲硫氨酸(N-甲酸化的)的密码子。
- A vitamin D receptor gene polymorphism in the translation initiation codon: effect on prote in activity and relation to bone mineral density in Japanese women. 更难理解的是为什么这些等位基因有时存在,有时不存在,有时甚至是相反的结果。
- A deletion of adenosine (A), at -241 (relative to initiation codon ATG), designated as Del(A) allele, was found in Laiwu compared with Yorkshire (GenBank accession number DQ463321-22). 克隆了猪DGAT1 5’调控区的部分序列(737 bp),在-241bp(相对于起始密码子ATG)发现一处由单个腺嘌呤(A)缺失产生的新SNP位点(定义为等位基因Del(A) ) (GenBank收录号:DQ463321-22);
- In this case, let's start earlier. 既然这样,我们就早点开始。
- I hope you can pardon his badness and let him start all over again. 希望您能原谅他的不好,让他从新开始。
- Effect of the Flanking Sequence Architecture of AUG,a Initiator Codon on Gene Expression Level in Rice 起译密码子AUG侧翼序列对水稻基因表达水平的影响
- The autumn or winter term start in September. 秋季或冬季学期九月份开始。
- It seems that his life is off to a new start. 看来他的生活有了新开端。
- How do you get start in that line of work? 你是怎么开始干那一行的?
- She woke up with a start when the door slammed. 关门声把她惊醒了。