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- BACKGROUND & OBJECTIVE: Full-length form of spleen tyrosine kinase [Syk(L)] is a tumor suppressor gene in breast cancer, which may translocate into cell nucleus and act as a transcriptional repressor. 背景与目的:全长型脾脏酪氨酸激酶[full-length form of spleen tyrosine kinase,Syk(L)]在乳腺癌中具有抑癌功能,可移位到细胞核内,作为转录抑制因子调节基因的转录。
- Relationship between the spleen tyrosine kinase and biological character of keloid fibroblasts 脾酪氨酸激酶与瘢痕疙瘩成纤维细胞生物学性状改变的关系
- Effect of spleen tyrosine kinase expression re-activation by inhibition of DNA methylation on oncogenesis growth of gastric cancer 脾酪氨酸激酶基因的再激活对胃癌生成和发展的影响
- spleen tyrosine kinase 脾酪氨酸激酶
- Spleen tyrosine kinase (Syk) 脾酪氨酸激酶
- The name is soluble f-m-s-like tyrosine kinase one? 这种蛋白质叫做可溶解fms样酪氨酸激酶一,
- Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer? PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用?
- The inhibitor of VEGF receptor tyrosine kinase was introduced in detail. 详细介绍了VEGF受体酪氨酸激酶抑制剂的研究进展。
- Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor. 苏尼替尼是一种新型的多靶点酪氨酸激酶抑制剂。
- The ABL gene encodes a tyrosine kinase whose activity is tightly regulated. ABL基因编码一种活性受到严格调控的酪氨酸激酶。
- FGFR3, a member of polypeptide growth factor family, is a tyrosine kinase receptor. FGFR3是这一多肽类生长因子的家族成员之一,它是一种酪氨酸激酶受体。
- The progress in tyrosine kinase inhibitor has been reviewed, including the chemical structures and the pharmacophore models. 本文综述了近年来酪氨酸激酶抑制剂的研究进展,包括抑制剂的结构和与激酶作用的药效团模型。
- AIM:To evaluate the relationship between spleen tyrosine k in ase(Syk)and the biological charcter of keloid fi broblasts(KFB)based on the research of signal transduction of keloid fibro blasts. 目的:通过瘢痕疙瘩成纤维细胞(KeloidFibroblasts,KFB)信号传递的研究,探讨脾酪氨酸激酶(SpleenTyrosineKinase,Syk)与KFB生物学性状改变的关系。
- Isoflavone. Inhibitor of EGFR tyrosine kinase, blocking phosphatidylinositol turnover. 异黄酮类。抑制EGFR酪氨酸激酶。阻断磷脂酰肌糖的翻转。
- STI571 could induce leukemia cells of ANLL into terminal differentiation by inhibiting c-kit tyrosine kinase. STI571对急性非淋巴细胞白血病原代细胞有诱导向同系终末分化的作用,对c-kit酪氨酸激酶有明显的抑制作用,且与药物浓度相关。
- Objective:To explore the mutation of receptor tyrosine kinase ( RET ) gene in sporadic medullary thyroid carcinoma. 目的:研究散发型甲状腺髓样癌酪氨酸激酶受体基因(RET)的突变情况。
- OBJECTIVE:To discuss the progress and the clinical application evaluation of protein tyrosine kinase(PTK) inhibitors. 目的:探讨酪氨酸激酶抑制剂的进展与临床应用评价。
- The structures and functions of EGFR as well as current status of EGFR tyrosine kinase inhibitors are reviewed. 综述了EGFR的结构和作用以及近年来EGFR酪氨酸激酶抑制剂的研究进展。
- Trastuzumab is a monoclonal antibody that directly targets part of the HER2 tyrosine kinase receptor. 曲妥单抗是一种直接针对HER2酪氨酸激酶受体的单抗。
- We got 10 phage clones which could bind with wild-type and mutant Bcr/Abl tyrosine kinase domain. (2)用菌体呈现随机7肽库对构建表达的激酶域蛋白进行了生物淘筛,得到了10个与两种类型激酶域均能结合的共用型噬菌体克隆。