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- AIM: To prepare the solid dispersions of angelica dahurica coumarins and measure their dissolution characteristics. 目的:制备白芷香豆素不同载体固体分散体,并检测其体外溶出特性。
- Results The solid dispersions prepared could improve the dissolution of the drug apparently compared with the original crystals of etodolac. 结果 与原料依托度酸制备的制剂相比,依托度酸固体分散体能明显加快药物的溶出;
- Results The results showed that the solubility of indirubin in solid dispersions prepared by cogrinding method were remarkably enh... 结论共研磨技术能有效地提高难溶药物的溶解度。
- OBJECTIVE To prepare sustained-release capsules Loaded with silymarin solid dispersions and to evaluate its releasing features in vitro. 目的:制备水飞蓟素固体分散缓释胶囊并考察其体外释放度。
- Powder X-ray diffractometry differential scanning calorimetry and scanning electron microscope were used to characterize the solid dispersions. 利用体外溶出度实验确定熔融法制备固体分散体的制备条件;
- Conclusion Dissolution in vitro of curcumin can been increased significantly by solid dispersions prepared with poloxamer 188 as carriers. 结论采用泊洛沙姆188制备的固体分散体能显著提高姜黄素的体外溶出度。
- Chutimaworapan S,Ritthidej GC. Effect of water-soluble carriers on dissolution characteristics of nifedipine solid dispersions[J].Drug-Dve-Ind-Pharm, 2000,26 (11 ): 1141. 翟光喜;毕殿洲;娄红祥;等.;磷脂固体分散体对槲皮素溶出促进作用的研究[J]
- Solid dispersion is able to release rapidly as an ameliorated technic. 固体分散体有速释作用,可考虑用固体分散技术改进降酶灵胶囊的制备工艺。
- Objective To optimize the method of preparing Dragon's blood solid dispersion . 目的确定制备龙血竭固体分散体的最佳方法。
- The solids dispersed in bubbles play a possibly significant role. 分散于气泡中的固体颗粒可能起着一种显著作用。
- Conclusion The sample of Galactosylglucose and Gliclazide can form solid dispersion by high speed grinding. 结论乳糖和格列齐特一定比例下经高速研磨混合的样品形成了共熔体;
- Abstract:Objective To prepare vinpocetine(VIN) solid dispersion(SD) and improve the dissolution profile of vinpocetine. 目的采用固体分散体技术改善长春西汀(VIN)的体外溶出特性。
- Objective To prepare the etodolac solid dispersion for enhancing its dissolution in vitro. 目的 制备依托度酸固体分散体,以提高依托度酸的溶出度。
- Objective To prepare apigenin (AP) solid dispersion and measure its dissolution in vitro. 目的 制备芹菜素固体分散体,并检测其体外溶出度。
- Conclusion The nifedipine-PEG solid dispersion could accelerate the in vitro drug dissolution. 结论 硝苯地平PEG固体分散体能加快药物的体外溶出速率。
- AIM Preparing the solid dispersion of anethole trithione so as to increase its solubility and dissolution rate. 目的制备茴三硫固体分散体,提高其溶解度和溶出速率。
- Objective:To improve the solubility and in vitro dissolution of isosorbide dinitrate(ISDN) solid dispersion. 目的:采用固体分散技术,提高硝酸异山梨酯在水中的溶解度和体外溶出速率。
- Conclusion The etodolac-PEG solid dispersion could enhance the drug dissolution in vitro. 结论 依托度酸PEG固体分散体能提高药物的体外溶出度。
- OBJECTIVE To prepare etoposide solid dispersion to enhance the dissolution rate. 目的制备依托泊苷固体分散体,改善依托泊苷的溶出度。