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- Keywords 8-methoxypsoralen-liposomal gel;skin permeation enhancer;transcutaneous absorption in vitro; 甲氧沙林;脂质体凝胶;透皮吸收促进剂;体外透皮试验;
- skin permeation enhancer 渗透促进剂
- Objective:To investigate penetration characteristics of artemether and the effect of different permeation enhancer on transdermal permeation of artemether through rat skin. 目的:考察蒿甲醚的体外透皮性能及几种常用中药促渗剂对蒿甲醚体外透皮性能的影响,为蒿甲醚经皮给药系统的开发奠定基础。
- Further, methanol precipitable solids from whole leaves of Aloe Vera L were used as permeation enhancer. 此外,还用完整的芦荟叶甲醇提取沉淀的固相物用于增进其渗透作用。
- RESULTS:The result showed that menthol helped enhance the skin permeation of Ketoconazole significantly(P<0.01). 结果:与不含促透剂的对照组比较,薄荷醇可显著提高酮康唑的经皮渗透(P<0.;01)。
- Conclusion The results demonstrate that the formation of an ion pair between KP and amine may be responsible for the enhanced skin permeation of KP using amine-EI system. 结论:结果表明,EI系统中有机胺对KP的经皮渗透有促进作用。这种渗透促进作用可能依赖于KP与胺之间所形成的离子对组成。
- Menthol binary eutectic mixture is the most effective enhancer, which has the greater transdermal flux of TMPH, suggesting that Borneol?Menthol eutectic mixture is a potent permeation enhancer. [结论]该低共熔混合物对盐酸川芎嗪经皮渗透具有明显促进作用,是一种较好的新型促进剂,具有良好的开发应用前景。
- OBJECTIVE: To investigate the effects of pH, donor phase drug concentration and Azone on in vitro skin permeation of dihydroetorphine hydrochloride (DHE) using excised abdominal Zaocys dhumnades (Cantor) skin. 目的:采用乌梢蛇腹部皮肤研究pH,药物浓度和月桂氮?酮对二氢埃托啡(DHE)体外透皮作用的影响。
- This product contains many herbal extractions, collagen and skin permeation to nourish skin and replenish water. It can remove tiny wrinkling caused by deficiency of nourishment and water. 补充肌肤所需微量元素,胶原蛋白及水份,加速衰老细胞脱落,维持肌肤营养和水份平衡。
- Methods Drug permeability through excised full skin of rats was determined by using side-by-side diffusion cells device, and plasticizer (triethyl citrate) or permeation enhancers as solvents. 方法采用双室水平扩散池,大鼠腹部全皮为渗透膜,分别以增塑剂柠檬酸三乙酯或经皮穿透促进剂为溶剂,测定药物的体外经皮透过性。
- Objectives: Study the influence of several different permeation enhancers on transcutaneous permeation of lidocaine hydrochloride gel to obtain an optimal formula. 目的:考察多种渗透促进剂对盐酸利多卡因凝胶经皮渗透的影响,并从中筛选其最佳处方组成。
- OBJECTIVE To probe the influence of the two kinds of permeation enhancers, azone and lepaloine on transdermal permeation of Compound hyperosteogeny patch(CHP). 目的探讨氮酮、杜香萜烯两种渗透促进剂对复方骨质增生贴剂透皮渗透的影响。
- The effectiveness of permeation enhancement of different enhancers was in the following order: 5% (m: m) azone>5% (m: m) isopropyl myristate>2.5% (m:m) azone>5% (m: m) oleic acid. 加入各种渗透促进剂后,促渗作用由大到小的排列顺序为:质量分数为5%25的氮酮>质量分数为5%25的肉豆蔻酸异丙酯>质量分数为2.;5%25的氮酮>质量分数为5%25的油酸;
- The boy booted the banana skin to the garbage heap. 男孩把香蕉皮踢到垃圾堆旁。
- Roughness of the skin can be caused by bad diet. 饮食不好可能引起皮肤粗糙。
- Her shoes chafed the skin on her feet. 鞋子擦破了她脚上的皮肤。
- OBJECTIVE To compare the permeation enhancing effect of fructus cnidii volatile oil and azone and to provide theoretic foundation for the application of fructus cnidii volatile oil. 目的对蛇床子挥发油和氮酮促透作用进行比较,为蛇床子挥发油的应用提供理论依据。
- Keywords anemonin;transdermal permeation;permeation enhancer;ethanol;laurocapm; 白头翁素;透皮吸收;促渗剂;乙醇;月桂氮酮;
- Keywords methyl salicylate;skin permeation;skin metabolism; 水杨酸甲酯;皮肤渗透;皮肤代谢;
- Heat sometimes causes a prickly rash on the skin. 热有时使皮肤上生剌痛的疹子。