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- simple tandem repeat(STR) 简单串联重复串联序列
- Keywords short tandem repeat(STR);X chromosome;haplotype;paternity testing; 短串联重复;X染色体;单体型;亲权鉴定;
- Abstract: Microsatellites are composed of simple tandem repeats of nucleotides primarily in non-coding gene sequences.The number of repeats is inherited as a codominant trait. 摘 要: 微卫星主要是指由非编码基因序列核苷酸的简单串联重复,其重复的数目呈共显性遗传。
- Keywords aneuploid;prenatal diagnosis;molecular biology;short tandem repeat(STR);fluorescence in situ hybridization(FISH); 非整倍体;产前诊断;分子生物学;短串联重复序列;荧光原位杂交;
- simple tandem repeat STR
- Objective:To analyze the genetic polymorphism of 9 short tandem repeat(STR) loci on chromosome 7p14-15 in Northeastern China Han population. 目的:分析东北汉族人群中7p14-15区域内9个短串联重复序列(STR)位点的遗传多态性。
- Methods The authors used a set of five Y-specific STR loci which were tetrameric tandem repeat loci chosen from the Genome Database. 方法无血缘关系样本采自成都地区汉族群体。
- Keywords Small tandem repeats(STR);Quantitative fluorescent PCR(QF-PCR);Chromosome aneuploides; 短串联重复序列;定量荧光PCR;染色体非整倍体畸变;
- It provides an experiment basis for combining highly genetic specificity of human euchromosome STR (Short Tandem Repeat, STR) with Y- chromosome STR study. 为结合具有高度遗传特异性的人类常染色体及Y染色体短串联重复序列(Short Tandem Repeat, STR)的研究,构建墓葬血亲关系深层次研究奠定了基础。
- Keywords multiplex amplification;Y-chromosome;short tandem repeats(STR);haplotype; 关键词复合扩增;Y染色体;短串联重复(STR);单倍型;
- A method based on PCR was developed to amplify short tandem repeat(STR) in combination with denaturing gradient gel electrophoresis (DGGE) and silver dyeing. 应用聚合酶链反应扩增STR,经变性凝胶电泳,再用银染显色方法,分析苯丙氨酸羟化酶(PAH)基因内含子3中TCTA重复序列的多态性。
- Objective To investigate the alleles and genotype frequencies of 6 short tandem repeat (STR) loci DXS7130, DXS1214, DXS6799, DXS6804, DXS7424 and DXS7133 on the X chromosome in Chinese Han individuals living in Shaanxi province of Northwest China. 目的研究陕西西安汉族人群6个位于X染色体上的短串联重复序列DXS7130、DXS1214、DXS6799、DXS6804、DXS7424和DXS7133等位基因及基因型频率分布。
- Objective To investigate the alleles and genotypes frequency of 10 short tandem repeat (STR) loci (DXS101,DXS6789,DXS6799,DXS6804,DXS7130,DXS7132,DXS7133, DXS7423, HPRTB, DXS8378)on X chromosome of Chinese Hui nationality population. 目的研究宁夏回族群体X染色体上的10个短串联重复序列(DXS101、DXS6789、DXS6799、DXS6804、DXS7130、DXS7132、DXS7133、DXS7423、HPRTB、DXS8378)的基因及基因型频率分布。
- Aim:To set up a method of prenatal diagnosis of classic phenylketonuria ( PKU) by linkage analysis of the short tandem repeat(STR) in intron 3 linked to the phenylalanine hydroxylase (PAH) gene. 目的:建立一种利用苯丙氨酸羟化酶(PAH)基因内含子3中短串联重复序列(STR)多态性连锁分析进行经典型苯丙酮尿症(PKU)产前诊断的方法。
- Short Tandem Repeat in PLA2G4C gene, which can be screened from blood samples, relates to the pathogenesis of glioma. PLA2G4C的短串联重复序列多态性与胶质瘤的发病有一定关系,并可通过血液标本进行此多态性的筛查。
- Brinkmann B,Klintschar M,Neuhuber F,et al.Mutation rate in human microsatellite:influence of the structure and length of the tandem repeat[J].Am J Hum.Genet,1998,62:1408. 庾蕾;伍新尧;李建金;等.;短串联重复序列遗传突变的观察[M]
- Allelotype analysis was done at five short tandem repeat markers (D17S855, D17S1322, D17S1323, D17S1326, and D17S1327) in or adjacent to BRCA1 on the recurrent mutation carriers. 对发现携带有相同突变的个体选取5个与BRCA1基因连锁的标记(D17S855、D17S1322、D17S1323、D17S1326和D17S1327)进行单倍型分析。
- Objective To investigate the allele frequencies of 6 short tandem repeats(STR) loci:D19S253,D14S306,D18S535,D11S2368,D12S391 and D4S2639 in the Han population of Henan province in China. 目的对河南省汉族群体的6个短串联重复序列(short tandem repeat,STR)基因座等位基因频率进行研究,获得河南汉族群体D19S253、D14S306、D18S535、D11S2368、D12S391、D4S2639基因座的群体遗传学数据。
- Objective: To investigate the polymorphisms of 3 short tandem repeats (STR) loci (CSF1PO, TPOX, TH01) in Maonan nationality in Guangxi province and to explore the origins of Maonan nationality. 摘要目的:调查广西毛南族人群3个短串联重复序列(STR)基因座CSF1PO、TPOX、TH01的遗传多态性,探讨广西毛南族人群的起源。
- Objective:To introduce the application of short tandem repeats in medicine. 目的:介绍短串联重复序列在医学中的应用。