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- serious hypertrophic scar 重度疤痕增生
- Objective To observe the therapeutic effects of capsaicin on hypertrophic scar( HS). 目的观察局部外用辣椒素对增生性瘢痕的治疗效果。
- METHODS: 76 cases of sheet hypertrophic scar patients were divided into two groups according to random method. 方法:对76例片状增生性瘢痕采用随机分组进行增生性瘢痕切除并刃厚皮片移植术;
- Objective To observe the effect of new type filling silicone cica-gel on hypertrophic scar. 目的:观察充填式加强型疤痕贴治疗增生性瘢痕的临床疗效。
- Objective To explore the effect of connective tissue growth factor in the pathogenesis of hypertrophic scar. 目的探讨结缔组织生长因子在增生性瘢痕发病机制中的作用。
- Purpose: Clinical evaluation of the color of hypertrophic scar entails quantitative measurements. 目的:临床评价增殖性瘢痕的颜色需要定量测量。
- A hypertrophic scar is a dermal phenomenon resulting from an imbalance in collagen production and maturation. 增生性瘢痕是以胶原过度沉积为特征的一种病理现象，其诱发的具体机理目前仍不清楚。
- Objective To explore the effect of connective tissue growth factor on the pathogenesis of hypertrophic scar and keloid tissue. 目的探讨结缔组织生长因子在增生性瘢痕和瘢痕疙瘩发病机制中的作用。
- Methods The expressions of MMP-2 and MMP-9 were detected by SP immunohistochemiccal technique in 20 keloid patients and 15 hypertrophic scar patients. 方法免疫组织化学SP法检测MMP-2、MMP-9在20例瘢痕疙瘩、15例增生性瘢痕及10例正常皮肤中的表达,采用图像分析技术对免疫组化结果进行定量分析。
- The formation of hypertrophic scar is an abnormal wound-healing response after thermal injuries or partial-thickness wounds. 因此,深入研究导致增生性瘢痕形成的创面修复失控环节,一直是创伤基础领域研究的焦点问题之一。
- On the other hand, sometimes they grow thick, tough, and corded, forming a hypertrophic scar or keloid, and may cause severe pruritus. 另一方面，也可增厚，变粗糙和如索状，形成肥厚性疤痕或瘢痕疙瘩，引起重度瘙痒。
- Conclusion: We should give priority to combined prevention and curing on the prevention and curing of faces hypertrophic scar. 结论：在面部烧伤后增生性瘢痕的防治中应优先选用综合防治方法。
- Objective: To study the effect of fungus Pathogenesis of surgical infection on the formation of hypertrophic scar in rabbits ears after injury. 目的:观察研究外科感染常见致病真菌对兔耳腹侧创面增生性瘢痕块形成的影响。
- CONCLUSION: High-dose carthamus tinctorius (500 g/L) could enhance the softening of hypertrophic scar of rabbit’s ears and increase compliance. 结论：高浓度红花液能促进兔耳增生性瘢痕的软化，组织顺应性增加。
- In a double-blind study versus placebo, Shimizu et al. verified the influence of Hirudoid cream in 41 patients with hypertrophic scar formation. 在一安慰剂对照的双盲研究中，Shimizu等人验证了喜疗妥软膏对41位患者疤痕形成的影响。
- The positive cellular rate of p-P38MAPK ascended in active hypertrophic scar, then decreased to a level which was still higher than that of normal skin. p P38MAPK的阳性细胞率在生长活跃的增生性瘢痕中升至最高 ;在成熟的瘢痕中虽有所下降 ;但仍明显高于正常皮肤(P <0 0 5 ) ;含有 p P38MAPK蛋白的细胞主要为表皮细胞和部分成纤维细胞。
- Methods The expression and activity of collagenase in hypertrophic scar and normal skin were studied with in situ hybridization and SDS-polyacrylamide gel electrophoresis. 方法应用原位杂交和SDS-聚丙烯酰胺凝胶加胶原底物电泳观测了肥厚性瘢痕组织中胶原酶表达、酶活性及胶原的降解。
- The fibroblasts from normal skin, hypertrophic scar and keloid were cultured, respectively, in vitro, and their morphologies and growth kinetics were compared. 结果发现，三类细胞的形态学方面没有明显差异，但瘢痕疙瘩成纤维细胞排列更加紊乱，极性消失，有交叉重叠现象。
- Objective This study was to investigate the in vitro cultivation, biological character- istics and ultrasturcture of the fibroblasts derived from normal skin, hypertrophic scar and keloid, to elu- cidate the value of their application. 目的探讨正常皮肤、增生性瘢痕和瘢痕疙瘩成纤维细胞的体外培养、生物学特征及超微结构,阐明其应用价值。
