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- rough sarcoplasmic reticulum 粗(糙)肌质网
- The sarcoplasmic reticulum is a system of intracellular membranes. 肌浆网属于细胞内膜系统。
- There was dilation and vacuolization of sarcoplasmic reticulum. 肌质网扩张、空泡化,溶酶体及脂滴增多;
- Effects of Hypoxic Acclimatization on Myocardial Sarcoplasmic Reticulum ATPase and ~(45)Ca~(2+) Uptake in Rats. 低氧习服对大鼠心肌肌浆网酶活性和钙摄取能力的影响
- Sarcoplasmic reticulum are well-developed and widely connect with mitochondria and nuclear envelope. 肌质网发达,与线粒休、核膜广泛联系。
- Objective To investigate the temperature effect of cold blood cardioplegia (CBC) on cardiac sarcoplasmic reticulum (SR) Ca2+ uptake and release. 评价冷血心肌麻痹液(CBC)温度对肌浆网(SR)Ca2+摄取和释放的影响。
- In the present study, rat cardiac sarcoplasmic reticulum(SR) phospholamban (PLB) phosphatase was partially purified by chromatography on DEAE-Sephacel. 用DEAE-Sephacel层析法部分纯化了大鼠心肌肌浆网phospholamhan(PLB)蛋白磷酸酶(PPase),并证明其是PPase-1。
- Myocardial sarcoplasmic reticulum (SR) Ca 2+ ATPase activity, SR Ca 2+ uptake, myocardial ATP and phosphocreatine (CrP) content were also measured. 测定心肌肌浆网(SR)钙ATP酶活性、心肌SR摄钙量、心肌组织ATP和磷酸肌酸(CrP)。
- Nishio M,Wasserstrom JA. Ouabain increases sarcoplasmic reticulum calcium release in cardiac myocytes[J]. J Pharmacol Exp Ther,2004, 308(3):1181. 韩玲,陈可冀.;黄芪对心血管系统作用的实验药理学研究进展[J]
- Sarcoplasmic reticulum is a principal subcellular organelle which regulates calcium homeostasis,protein synthesis,and apoptosis of cardiomyocytes. 肌浆网是调控心肌细胞钙稳态、蛋白质合成和细胞凋亡的重要亚细胞器。
- The effects of plasmid pcDNA3 on Ca2+ transport of sarcoplasmic reticulum (SR) in ischemic skeletal muscle was investigated. 在大鼠肢体缺血模型上观察了质粒pcDNA3对缺血骨骼肌肌浆网(SR) Ca2+转运的影响。
- Objective To study the role of sarcoplasmic reticulum calcium adenosine triphosphatase (Ca 2+ ATPase) and phospholamban in patients with diastolic heart failure (DHF). 目的 研究肌浆网钙泵和磷酸受纳蛋白在舒张性心衰 (DHF)患者心肌细胞内 Ca2 +调节中的作用。
- Objective: To evaluate influences of regular dose of adriamycin (ADR) on heart function and sarcoplasmic reticulum (SR) Ca 2+ ATPase in cardiomyocyte of rabbits. 目的 :探讨治疗剂量阿霉素 (ADR)对心脏血流动力学及心肌肌浆网 Ca2 + - ATP酶活性的影响。
- In normal cardiac muscles, phospholamban can be phosphorylated at distinct sites by various protein kinases and release its inhibition to sarcoplasmic reticulum Ca2+ ATPase. 正常情况下,受磷蛋白可被不同的蛋白激酶磷酸化从而解除其肌浆网钙ATPase的抑制作用。
- Abstract: Phospholamban (PLB) is a prominent regulator of myocardial contractility and a reversible inhibitor of the cardiac sarcoplasmic reticulum Ca2+ ATPase activity. 受磷蛋白(phospholamban)是心肌收缩的一个重要调节因子,可抑制心肌肌浆网钙ATPase的活性、降低其对钙的亲和力。
- Ryanodine receptor (RyR), a calcium release channel within the sarcoplasmic reticulum (SR) membrane, is a key protein in skeletal and cardiac excitation-contraction coupling. Ryanodine受体(ryanodine receptor, RyR)是位于细胞内肌质网(sarcoplasmic reticulum, SR)膜上的钙释放通道,是骨骼肌和心肌细胞兴奋-收缩偶联过程中的关键蛋白。
- Block of T-type calcium channel may inhibit the calcium over-load by improving the function of releasing and absorbing calcium of sarcoplasmic reticulum. 阻断T型钙通道,可能通过改善肌浆网摄取及释放钙的功能而抑制心肌细胞钙超载。
- OBJECTIVE To explore effect of astragalus membranaceus on phospholamban and Ca~(2+)-ATPase,and observe variation of the sarcoplasmic reticulum PLB and SERCA in the myocardium in spontaneously hypertensive rats at the early hypertension. 目的:观察自发性高血压大鼠(spontaneously hypertensive rats,SHR)在高血压早期心肌肌浆网中的钙泵(Ca2+-AT-Pase,SERCA)和受磷蛋白(PLB)在蛋白水平表达量的变化,探讨黄芪注射液对SHR心肌PLB和SERCA表达的影响。
- RyR is one kind of Ca~(2+) channels existed in endoplasmic reticulum (ER) / sarcoplasmic reticulum ( SR) of cells, which is composed of four subunits, and its higher structure is tetraploid. RyR是一种存在于细胞内质网(endoplasmic reticulum,ER)/肌浆网(sarcoplasmic reticulum,SR)上的Ca~(2+)通道,由4个亚单位组成,高级结构为四聚体。
- The result under electronmicroscope showed that the mitochondrion of muscle fiber increased in number,the sarcoplasmic reticulum and transverse tubule decreased and developed poorly. 电镜下肌纤维线粒体多,三联管结构少、发育差;病变肌纤维呈细胞水肿和肌原纤维破坏的表现;