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- retinoblastoma gene(Rb gene) 视网膜母细胞瘤基因, Rb基因
- These facts suggest that MDM2, p53 and Rb gene harmonize in the tumorigenesis and progression of bladder TCC. 他们在膀胱TCC的发病过程中都发挥了一定的作用,而且相互配合相互影响;
- The negative or absent rate of Rb gene in lung cancer and normal lung tissues were 23. 3% (14/60) and 6. 3% (2/32) respectively ( P < 0. 05 ). 抑癌基因Rb在正常组织与肺癌组织中的表达缺失率分别为6.;3%25(2/32)和23
- We should be pride as ophthalmologist that it is the RB gene that contribute to the entire medical science on cancer pathogenesis and genetics. RB基因对于肿瘤发病机理和遗传学的具有的重大意义,是眼科学家们可以为自豪的。
- As RB gene is the first identified tumor suppressor gene, the finding has reolutionalized our understanding of cancer pathogenesis, so this huge interest is understandable. 由于RB基因是首先发现的抑癌基因,使我们对于肿瘤的发病机理有了全新的认识,其重大意义是可以理解的。
- The Rb gene abnormality was one of the hereditary factors associated with the occurrence of lung cancer, and the abnormal Rb gene was found in 90% of small cell lung cancer (SCLC) and 10 -30% of non - small cell lung cancer ( NSCLC). 在小细胞肺癌(SCLC)约90%25,非小细胞肺癌(NSCLC)约10-30%25存在Rb基因异常,Rb基因异常者因肺癌死亡的危险性比正常人高15倍,是肺癌发生的遗传因素之一。
- Experimental research on apoptosis of retinoblastoma transplantation tumor induced by Rb gene Rb基因诱导视网膜母细胞瘤移植瘤细胞凋亡的实验研究
- p16 INK4a is one of the inhibitors of cyclin dependent kinase(cdk),which inhibits cdk4/cdk6 mediated phosphorylation of retinoblastoma gene product (Rb) that leads to cell cycle arrest in G 1 phase. p16 INK4a是一种细胞周期蛋白依赖激酶 (cdk)的抑制因子 ;它通过抑制cdk4与cdk6的活性 ;使视网膜母细胞瘤抑制蛋白Rb处于低磷酸化状态 ;从而使细胞阻滞于G1期 .
- A study on the deletion and mutation of Rb gene in lung cancer 视网膜母细胞瘤易感基因在人肺癌中的缺失和突变研究
- Adenovirus-mediated Rb Gene Transfect for Head and Neck Cancer 外源性Rb基因转染对头颈肿瘤的抑制作用
- Advances in the Study of Rb Gene and Cell Senescence Rb基因与细胞衰老的研究进展
- The Expression of Rb Gene in the Developing Kidney of Embryo Mouse Rb基因在小鼠胚胎发育中期肾组织的表达
- Keywords Cyclin E;Retinoblastoma gene;Cervical intraepithelial neoplasm;Cervical squamous cell carcinoma; 细胞周期素E;视网膜母细胞瘤基因;子宫颈上皮内瘤变;子宫颈鳞状上皮癌;
- Objective To study the CT findings and clinical features of retinoblastoma(RB). 目的分析视网膜母细胞瘤的CT和临床特征。
- Squamous cell carcinoma of lung correlated with human papillomavirus and protein expression of tumor suppressor gene Rb 肺鳞癌与人乳头瘤病毒及抑癌基因Rb蛋白表达的关系
- Significance of Genetic Alterations of the RB Gene in Colorectal Tumorigenesis RB基因异常改变在大肠癌发生、发展中的意义
- Objective To investigate the killing effect of herpes simplex virus thymidine kinase/gancyclovir (HSV tk/GCV) suicide gene therapy system on retinoblastoma (Rb) cells and the mechanism of bystander effect. 目的 研究单纯疱疹病毒胸腺嘧啶核苷激酶 /更昔洛韦 (herpessimplexvirusthymidinekinase /gancyclovir,HSV tk/GCV)自杀基因系统对视网膜母细胞瘤 (retinoblastoma ,Rb)细胞的体外杀伤作用以及旁观者效应发生的机制。
- retinoblastoma gene Rb gene
- Objective Observe and analyze the pathology and clinic of retinoblastoma(Rb).Methods Observe the pathological pattern and clinic. 目的观察分析视网膜母细胞瘤的病理形态和临床表现。
- Pathologic examination confirmed a case of retinoblastoma. 核磁共振检查更察觉松果腺有一肿瘤。