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- The micro residual disease (MRD) of case 2 and 3 disappeared after DLI. 例2、3经过DLI后消除了微小残留病,除例5仍然为混合性嵌合体和进步状态外,4例均达血液学完全缓解。
- WT1 is related to the prognosis of AML and uses as a marker in detecting the minimal residual disease. 认为WT1基因和急性髓细胞白血病(AML)的预后有关,可以作为微小残留病检测的标记;
- Postoperative irradiation may be beneficial in slowing the progression of residual disease. 术后的放射线治疗可以减缓残存肿瘤的恶化。
- Therefore, WT1 gene is a new prognostic factor and a new marker for the detection of minimal residual disease in AL. WT1基因是一个有用的预后指标与检测微小残留病的标记。
- Monitoring the bcr/abl fusion gene by RT-nested-PCR can be used to evalute the efficacy of the therapy and detect the minimal residual disease(MRD). RT -nestedPCR方法检测bcr/abl融合基因可以作为临床诊断、判定预后的指标 ,适用于微小残留病变的监测
- Conclusion Monitoring of the WT1 gene by Nest RTPCR would be a surely marker for the detection of minimal residual disease (MRD) in acute leukemia. 结论 用Nest、RT-PCR测定WT1基因的表达可作为检测白血病微小残留病(MRD)的一项指标。
- In a review of 1,175 radical prostatectomies, Libertino and colleagues identified a subset of 534 patients with residual disease. 利伯提诺的研究小组对1,175名做过根治性前列腺切除术的病人进行了分析,发现其中有534名病人有残留病灶。
- Still, small volume or minimal residual disease has been recogenized as a potentially suitable target for radiolabeled antibodies.RIT... 虽然如此,放射性核素标记的抗体在治疗微小病灶中的应用前景看好。
- Objective To improve the clinical significance of detecting minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL). 目的为提高急性淋巴细胞白血病(ALL)微小残留检测的临床意义。
- The quantitative assessment of WT1 expression in peripheral blood samples by FQ-RT-PCR may be a useful tool for monitoring minimal residual disease. 对外周血WT1基因表达进行定量分析,可用于微小残留病的监测。
- Surgery was performed after the6 th course and gross residual disease was seen in28 patients. FDG standardized uptake values did not vary much in this group. 手术于第六疗程后进行,28名患者发现残留病变组织。该组中FDG标准值并未改变很多。
- Objectives To investigate the clinical significance of AML1/ETO fusion mRNA in diagnosing and monitoring of minimal residual disease and its prognostic value. 目的 研究AML1/ETO融合mRNA在儿童急性髓性白血病M2型中的表达及其对残留白血病监测及预后的指导意义。
- Minimal residual disease (MRD) as a marker of antileukemic drug efficacy is being used to assess risk status and, in some cases, to adjust the intensity of therapy. MRD作为抗白血病药物疗效标志,被用于评估患者危险,在某些病例中也用于调整治疗强度。
- Minimal residual disease (MRD) is defined that there are residual leukemia cells in the range of 10~6-10~8 in the patients who are in complete remission (CR). 患者经治疗后,达到临床和血液学的完全缓解,体内仍有106-108个残留白血病细胞,称为微小残留病(minimal residual disease, MRD)。
- Objective To explore the clinical significance of quantitative analysis of minimal residual disease (MRD) cells DNA in children with acute lymphoblastic leukemia (ALL). 目的探讨定量监测儿童急性淋巴细胞白血病(ALL)微量残留病(MRD)细胞DNA变化的临床意义。
- Objective To discuss the significance of minimal residual disease detection in acute B-lymphoblastic leukemia, Surface differentiation antigen CD45- leukemic cells were detected. 目的探讨细胞表面分化抗原45阴性(CD45-)白血病细胞在急性B细胞性白血病微小残存病变监测中的意义。
- Surgery was performed after the 6th course and gross residual disease was seen in 28 patients. FDG standardized uptake values did not vary much in this group. 手术于第六疗程后进行,28名患者发现残留病变组织。该组中FDG标准值并未改变很多。
- Surgery was performed after the 6th course and gross residual disease was seen in 28 patients. FDG standardized uptake alues did not ary much in this group. 手术于第六疗程后进行,28名患者发现残留病变组织。该组中FDG标准值并未改变很多。
- His disease was complicated by pneumonia. 他的病因肺炎并发症而变得更严重。
- There was high level expression of CD 117 in acute promyelocytic leukemia. Minimal residual disease of APL can be detected using multi-color flow cytometry to analyze the expression of CD 117 , CD 34 and HLA-DR. 提示 :APL患者有较高水平的CD117表达 ,CD117与CD34 、HLA DR联合进行多色流式细胞术分析 ,可用于APL微小残留病灶的检测。