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- To this end, advances have been made in the areas of cell transplantation and in the development of recombinant viral vectors for gene delivery. 该研究结束时,在细胞移植和为基因传输所进行的重组细胞病毒载体研发这两方面取得了进展。
- Keywords Japanese encephalitis virus;pseudorabies virus;gene cloning;recombinant viral vector vaccine; 乙型脑炎病毒;伪狂犬病病毒;基因克隆;重组病毒载体疫苗;
- recombinant viral vector 重组病毒载体
- Insert and ligate any DNA fragment into a vector such as plasmid or viral vector, to form a recombinant DNA. 通常重组DNA一词指的是将任何细胞来源的DNA片段接在染色体外的能迅速复制的质粒或病毒载体。
- AIM:To study the safety of intramuscular injection of non viral vector pNMG3 of recombinant human growth hormone gene(hGH). 目的:研究携带重组人生长激素(hGH)基因非病毒载体pNMG3骨骼肌注射方法的急性期安全性。
- Vector retargeting is one of the important strategies on viral vector targeting. 载体的靶向策略很多,载体重靶向就是其中重要的一种。
- Novel vaccines for veterinary use are the fovus of immunology and virvology.They are mainly subunit vaccines,gene delete vaccines,recombinant viral vaccines,genetic vaccines. 新型兽用疫苗是免疫学和病毒学的研究热点,主要包括亚单位疫苗、基因工程缺失苗、重组病毒活载体疫苗和基因疫苗。
- The different of the two plasmid lies in different Promotors,since a strong promotor may paly a important role in gene expression in viral vector. 他们的区别在于含有不同的启动子,因为强启动子可能在病毒载体系统的基因表达上起关键的作用。
- Gene therapy researchers have found that a popular viral vector used to * disease-curing genes into mice has a dangerous down side: it can apparently trigger liver tumors. 基因治疗的研究者们已经发现一个常用来插入治病基因的病毒载体有危险的副作用:明显地,它能够导致肝癌的发生。
- Viral Vectors for Gene Therapy-Methods and Protocols. 病毒载体在基因治疗中的应用。
- Thus, overexpression of the glucose transporter gene via the introduction of a herpes simplex viral vector into the nervous system protected neurons from focal ischemic injury (64). 这样,葡萄糖载体基因的过度表达通过疱疹单一腺病毒载体进入到神经系统,保护神经元不受局部缺血损伤(64)。
- Thus, overexpression of the glucose transporter gene via the introduction of a herpes simplex viral vector into the nervous system protected neurons from focal ischemic injury(64). 在其他的研究中,研究人员用携带腺病毒载体把"治疗"基因带入中枢神经系统。
- One study has already shown that it is possible to inject a viral vector for the vasopressin receptor into the brains of the fickle meadow voles and make them better partners and parents. 一项研究显示:将一种抗利尿激素受体的病毒载体注射入“花心的”草甸田鼠的大脑中,会使它们成为更好的伴侣和父母。
- recombinant viral macrophage inflammatory protein 重组病毒巨噬细胞炎性蛋白
- The Asklepios researchers plan to insert a proprietary miniaturized version of the dystrophin gene into an adeno-associated viral vector designed to deliver the gene to human muscles. 目前没有使肌肉停止病变和逆转的有效的治疗方法。
- Recombinant viral inflammatory protein-Ⅱ 重组vMIP-Ⅱ
- Vector tropism is a research hot spot in cancer gene therapy, and targeted viral vectors play a key role in the enhancement of safety and efficiency in cancer gene therapy. 病毒载体的靶向性问题是肿瘤基因治疗中的重要研究热点,靶向病毒载体是提高肿瘤基因治疗安全性和有效性的重要途径。
- In other studies, viral vectors have been used to introduce "therapeutic" genes into the central nervous system. 在其他的研究中,研究人员用携带腺病毒载体把"治疗"基因带入中枢神经系统。
- The RNA copies of viral vectors and mRNA levels of target genes were determined by quantitative real-time RT-PCR. 病毒RNA分子拷贝数和靶基因mRNA水平用实时定量RT-PCR确定。
- Pseudotyped viral vectors will provide novel opportunities for the study of gene therapy. 假型病毒载体将会给基因治疗研究带来新的机遇。