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- Objective: To study the expression changes of serotonin transporter (SERT) in the rostral raphe nuclei of postmortem brainstem in alcoholic human. 摘要目的:观察酗酒人脑标本脑干头侧中缝核群5-羟色胺转运体(SERT)的表达变化。
- Combining the immunogold-silver staining method and the image quantitative analysis, aging changes in serotonin-like (5-HTL) neurons of the raphe nuclei of the brainstem were observed in young (2 months), adult (10 months) and old (24 months) Wistar rats. 本文结合免疫金银染色(IGSS)法和图像定量分析,观察了幼年(2个月)、中年(10个月)和老年(24个月)Wistar大鼠脑于中缝核群5-羟色胺样(5-HT-LI)神经元的衰老变化。
- The dorsal raphe nucleus and auditory and vestibular pathway. 与听觉、前庭系统相关的中缝背核神经通路研究进展。
- Median raphe nucleus did not show the decreased SERT labeling. 中缝正中核SERT标记强度未见显著降低。
- Retrograde tracing revealed that regenerated axons originated from brain stem nuclei, including red nucleus, locus coeruleus, raphe nucleus, vestibular nucleus, and reticular formation. 神经逆向追踪结果证实移植细胞后可帮助上脊髓神经核包括红核、蓝斑核、缝核、前庭核及网状结构内的神经元再生。
- The administration of L-NNA (ica) showed a lot of 5-HT immunoreactive cells in the dorsal raphe nucleus. 脑室给予L-NNA使中缝背核5-HT神经元阳性细胞增多。
- Results In comparison with healthy group, SERT decreased in dorsal raphe nucleus, substantia nigra and striatum in PD brains. 结果与健康组比,PD人脑标本中缝背核、黑质以及纹状体的SERT标记信号呈不同程度降低。
- Keywords serotonin;aminobutyric acids;raphe nuclei;dorsal;rat 血清素;氨基丁酸类;中缝核;背侧缝核;大鼠;
- Objective To investigate the expression of FOS and the positivity of NADPH-d test in the dorsal raphe nucleus of morphine withdrawal rats. 目的研究吗啡戒断大鼠中缝背核FOS、NADPH-d酶表达的变化。
- Serotonin normally arrives in the frontal cortex by way of the raphe nucleus, a structure that also communicates with the locus coeruleus. 血清张力素除了其他的作用外,对于情绪及睡眠周期的调节也可能相当重要。
- The dark cell nucleus and light cell cytoplasm of FLI cell body were examined in frontal cortex V, mesencephalic reticular formation and dorsal raphe nucleus in BD rat. 额皮质V层、中脑网状结构和中缝背核内见到胞核深染、胞浆浅染的FLI神经元胞体。
- Serotonin neurons originate in the raphe nucleus, near the base of the brain and, with long, threadlike extensions known as axons reach more distant regions. 羟色胺神经元产生于中缝核,该核靠近大脑基底部。这种神经元带有像线一样伸展很长的轴突,达至很远的区域。
- Methords Immunocytochemistry and histochemistry methods were used to study the changes of FOS and NADPH-d positive neurons in the dorsal raphe nucleus of morphine withdrawal rats. 方法运用免疫组织化学、组织化学方法观测吗啡戒断大鼠动物模型中缝背核FOS、NADPH-d酶表达的变化。结果吗啡戒断组FOS、NADPH-d阳性神经元、纤维和终末表达明显增加(P<0。
- The content of 5-HT and 5-HIAA in PAG,bulbar raphe nucleus and spi-nal cord were markedly increased during acupuncture analgesia. With the exceptionof PAG,the appearance of 5-HT and 5-HIAA increase was later than that of NA. 电针镇痛时,PAG、延脑中缝核区和脊髓的5-HT 和5-HIAA 含量均有显著增加,除 PAG 外,这种增加的出现较 NA 为晚。
- Located or occurring between nuclei. 核间的位于或发生于核之间的
- Fos immunoreactive cells were mainly located in the dorsal raphe nucleus (DR),nucleus raphe magnus (NRM), locus coeruleus (LC), the ventrolateral of periaqueductal gray (vlPAG), hypothalamic paraventricular nucleus (PVN). Fos阳性细胞主要分布于中缝背核 (DR)、中缝大核 (NRM )、蓝斑 (LC)、中脑导水管周围灰质腹外侧 (vlPAG)和下丘脑室旁核。
- When they treated mice with Mycobacterium accae they found that it did indeed actiate a particular group of brain neurons that produce serotonin - in the interfascicular part of the dorsal raphe nucleus (DRI) of the mice, to be precise. 在用牝牛分枝杆菌处理小鼠后,他们发现这种细菌确实能够刺激一类能产生5-羟色胺的特殊神经元,更准确的说是位于小鼠中缝背核束间。
- It receives dopaminergic innervations from ventral tegment area and SNc, and noradrenergic and serotonergic innervations from the locus ceruleus (LC) and dorsal raphe nucleus (DRN), respectively. 腹内侧前额叶皮层主要接受来自腹侧被盖区(ventral tegmental area,VTA)和SNc的DA能神经纤维投射,以及来自蓝斑的去甲肾上腺素(noradrenaline,NA)能和中缝背核的5-HT能神经纤维投射。
- The results indicate that the sleep-suppressive effects induced by inhibition of nitric oxide synthase may be mediated via the activition of 5-HT neurons in the dorsal raphe nucleus. 提示一氧化氮合成抑制所致的睡眠抑制可能与中缝背核5-HT神经元免疫阳性反应增强有关。
- Abstract The effect of dorsal raphe nucleus (DR)stimulation on the unit discharge of suprachiasmatic nucleus (SCN) neurons was studied and analyzed pharmacologically in the Wistar rats. 进行药理学分析。