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- AIM:To explore the recombined human proinsulin gene containing glucose reaction element(GLRE) expression in transfected CBRH7919 cells. 目的:探讨含有葡萄糖反应元件的重组人胰岛素原基因在培养的大鼠肝癌细胞中基因转移及表达情况。
- Conclusion Naked plasmid with mutant human proinsulin gene is successfully transfected into diabetic mice, which show the singificant short-term effect of decreasing blood glucose. 结论含有人胰岛素原突变基因的裸质粒成功转染糖尿病小鼠,并有显著的短期降血糖效应。
- Construction of a mutant human proinsulin gene with signal peptide code and detection of its expression in COS-7 cells 带信号肽人胰岛素原突变体的构建及在COS-7细胞中的表达
- Keywords human proinsulin gene;retroviral vector;gene recombination;gene expression; 人胰岛素原基因;逆转录病毒载体;基因重组;基因表达;
- Keywords diabetes mellitus;proinsulin gene;gene therapy;intramuscular injection;naked plasmid; 糖尿病;胰岛素原基因;基因治疗;肌肉注射;裸质粒;
- Construction and identification of recombinant defective retroviral vector with mutant human proinsulin gene and stable virus-producing cell lines 人胰岛素原突变体重组逆转录病毒及稳定包装细胞系的构建和鉴定
- Gene therapy for diabetes mellitus: construction and identification of eukaryotic cell expression plasmid in rat proinsulin gene 糖尿病的基因治疗技术:大鼠胰岛素原基因真核细胞表达质粒构建与鉴定
- proinsulin gene 胰岛素原基因
- The position that a given gene occupies on a chromosome. 基因座在一条染色体上某种给定基因所占的位置
- Half of the people who inherit the gene express it. 半数有这种遗传基因的人,皆显示出其影响
- Proinsulin is formed in rough endoplasmic reticulum. 胰岛素原在粗糙型内质网中合成。
- Now the variant of each gene is called an allele. 每一种基因的变化就叫做等位基因。
- A gene fragment encoding three copies of proinsulin C peptide was synthesized and expressed in E. 合成了胰岛素原C肽三聚体的基因,并在大肠杆菌中得到高效表达。
- We know a lot about the structure of gene now. 如今我们对基因的结构有了较多的了解。
- A single gene may have many effects. 单一基因可能具有很多种效应。
- There can be more than two alleles for a gene. 一个基因可能有两个以上的等位基因。
- A mutable organism; a mutable gene. 一个易变的生物;一个易变的基因
- Proinsulin was an independent affective factor of insulin resistance. 胰岛素原水平是胰岛素抵抗的独立相关因素。
- Gene Shepard: That was a 35 dollar belt! 吉恩·谢帕德:那地方可值35美元呢!
- Gene Shepard: That was a35 dollar belt! 吉恩·帕德:那地方可值35美元呢!