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- In recent years, phage display was considered for vaccine development. 近年来，呈现噬菌体开始应用于疫苗的研究。
- Here, the basic mechanism and the application of phage display random peptide libraries are briefly introduced. 本文简介此类文库的基本作用原理及应用。
- Objective To screen polypeptides binding to human CD137 by biopanning phage display random heptapeptide library. 目的应用噬菌体随机七肽库筛选与人CD137特异结合的肽序列。
- T1 phage displayed a higher survival than poliovirus. T1噬菌体的存活高于脊髓灰质炎病毒。
- Aim The phage display antibody library was constructed to obtain functional anti Fas Fab. 目的构建噬菌体抗体库,获得具有功能的抗Fas?Fab噬菌体抗体。
- Objective To search for new antigens expressed on the surface of thymic stromal cells using phage display technology. 目的利用噬菌体展示技术寻找胸腺基质细胞表面的新抗原。
- Phage display random peptide library is a kind of polypeptide library developed by filamentous bacteriophages. 摘要噬菌体随机展示肽库是一类利用丝状噬菌体发展起来的多肽文库。
- Objective To screen two MUC1 antigen mimic epitopes by phage display peptide library technology. 目的从噬菌体表面展示的随机12肽库中筛选出MUC1抗原的模拟表位。
- Phage display technology is an ideal approach to the study on the protein evolution. 噬菌体展示肽库技术是研究蛋白质分子进化的理想工具。
- With the development of phage display libraries, it might be applied extensively in many fields of research. 随着此项技术的不断完善和发展，噬菌体肽库已在许多领域得到了广泛的运用。
- Methods mRNA was extracted from lymphocytes of a volunteer with high level antibody to HBsAg. Fab phage display library was constructed. 方法 采用噬菌体抗体库技术 ,从乙肝疫苗免疫后健康人外周血淋巴细胞中提取抗体基因建立抗体库 ,用纯化的HBsAg筛选Fab抗体 ;
- Ke Shen, et al. Bio-panning of HGV antigen epitope from a phage display library. Progress in Natural Science. 2000;10（6）:446-450. 柯屾，等。核糖体展示技术。见：分子文库-中国生物技术丛书。沈倍奋主编。2001。北京：科学出版社。
- Conclusion The phage display technique can be applied to study the viral antigenic peptides with the advantages of simple, accuracy and rapidity. 结论噬菌体展示技术完全可应用于病毒蛋白抗原序列的筛选，并具有简便、快速、准确的优点。
- The phage display antibody library is developed by reasonably combining the antibody library technology and phage surface display system. 将抗体库技术与噬菌体表面展示系统有机地结合就发展成为噬菌体展示抗体库。
- Objective To find the site of the insulin binding with the insulin receptor via biopanning of disulfide constrained phage display heptapeptides library. 目的用肽库筛选技术寻找与胰岛素受体结合的胰岛素位点。
- Utilizing the technology of phage surface display, special antibody can be gained from the human naive Fab phage display library, which can be used as a new therapy for tumors. 本研究构建的人天然Fab段噬菌体抗体库可为进一步筛选特异性抗体,用于免疫治疗打下基础。
- Based on the results of phage display, the interactions between three glyco replica peptides and glucoamylase were investigated by molecular dynamics simulation. 基于噬菌体展示的结果,对三种拟糖多肽与葡糖淀粉酶的相互作用进行了分子动力学模拟。
- By using combinatorial library and phage display technologies on a hapten-specific antibody we were able to demonstrate that a peripheral carrier imprint indeed exists. 利用组合库和噬菌体展示技术，我们证明半抗原特异性抗体确实存在有外围载体的某些遗迹。
- Using phage display, we can fix on antigenic determinants and find the characteristic sequences that the proteolytic enzymes act and the site proteins interacting together. 用噬菌体展示技术不仅能够确定抗原决定簇,蛋白水解酶作用的特征序列,以及蛋白质之间的相互作用的位点等等,还可以用来筛选一些非肽分子(特别是糖)的模拟物。
- Conclusions The method of screening the antagonist of receptor of PGE2 by phage display is applicable, while this peptide can play the anti-inflammation role. 结论:噬菌体筛选PGE2受体拮抗剂的方法可行，并且得到的环七肽具有一定的抗炎作用。
