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- p70 S6K p70S6K
- Two signaling cascades had emerged as major players in the AngII-induced vascular endothelial cell proliferation: the PI3K-p70 S6K cascade and the Ras-p42/p44 MAPK cascade. 结论:(1)慢性CsA肾病肾移植患者肾组织局部RAS活化,CsA刺激血管内皮细胞分泌AngII,蛋白质合成增加。(2)AngII刺激血管内皮细胞蛋白质合成增加通过激活PI3K-p70 S6K和Ras-p42/p44 MAPK两条信号通路。
- METHODS: BMDCs were stimulated by CpG ODN in combination with tumor antigen (TAg). The expression of CD80 on BMDC surface was analyzed by FCAS. Level of IL-12 (p70) in supernatants of BMDC culture was detected by ELISA. 方法 :CpGODN联合肿瘤抗原 (TAg)体外刺激BMDC ,流式细胞术检测受刺激BMDC表达CD80的阳性率 ,ELISA检测受刺激BMDC分泌IL - 12 (p70 )的水平 ,MTT法检测活化BMDC刺激T细胞的增殖能力 ,联合CpGODN和TAg体内预激小鼠获得CTL ,检测CTL对肝癌细胞株Hca-F的特异性杀伤作用。
- P70 S6 Kinase Activated by Insulin and PMA Through Distinct Pathways in Protein Synthesis 胰岛素和佛波酯在蛋白质合成中经不同途径激活p70 S6激酶
- p70 S6 kinase 核糖体蛋白S6激酶
- The mean serum level of IL-12(p70) was 19.44 pg/ml in combined bacterin group, 12.41 pg/ml in Staphylococcus aureus group, 10.35 pg/ml in Salmonella typhimurium group, 11.68 pg/ml in Mycobactoria phlei group, and 4.45 pg/ml in control group; D组小鼠血清IL-12(p70)的平均含量最高(19.;44pg/ml);A、B、C组IL-12(p70)的平均含量分别为11