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- p38 MAPK pathway p38MAPK通路
- MAPK pathway minimally consists of a MAPKKK-MAPKK-MAPK module. MAPK讯息传递路径主要藉由MAPKKK-MAPKK-MAPK模式所引发下游的级联反应。
- PTP is a negative regulating factor in the MAPK pathway. MAPK级联途径参与有机体的发育、细胞增殖、激素调节以及逆境胁迫的信号转导, PTP在MAPK级联途径中主要起负调控作用。
- ATF-2,one of substrates of p38 MAPK,mediated iNOS gene transcription induced by p38 MAPK. p38 MAPK底物转录因子ATFZ,介导了 p38 MAPK对rOS启动子的转录
- Vincristine could affect the activity of p38 MAPK in gastric cancer cell SGC7901 and multidrug resistant cell SGC7901/VCR. p38MAPK信号转导途径可能与长春新碱的抗肿瘤活性相关 ,肿瘤细胞内 p38MAPK对长春新碱刺激的反应速度可能与胃癌长春新碱耐药相关
- So we are further to examine whether AOPP enhances osteoblastic differentiation of vascular smooth muscle cells via MAPK pathway. 另外,分裂原激活的蛋白激酶(mitogen-activated protein kinase, MAPK)家族的信号转导通路,特别是其中的ERK1,2途径,主要介导细胞增殖和分化的信号转导。
- Objective To study the effect of gastrin on the mRNA and protein expression of urokinase-type plasminogen activator (u-PA) in human colon cancer cells and detect the role of p38 MAPK in this process. 目的研究胃泌素对人结肠癌细胞尿激酶型纤溶酶原激活物(u-PA)mRNA和蛋白表达的影响,探讨信号分子p38 MAPK在其中的作用。
- METHODS: We used immunohistochemical ABC and Western blot method to detect the expression of p38 MAPK in lung tissues and airway epithelial cells in acute lung injury rat model and observed the influence of N acetylcysteine (NAC) on the expression. 方法 :采用免疫组织化学ABC法和Western blot技术 ;检测磷酸化的 p38MAPK在大鼠急性肺损伤模型气道和肺组织的表达 ;并同时观察N 乙酰半胱氨酸 (NAC)对其表达的影响 .
- In this paper, we review the recent advances in study of PTP and the role of MAPK in plants, including the structure of PTP and its functions in the MAPK pathway, especially in Arabidopsis thaliana. 本文就PTP的结构和功能、MAPK在植物中的作用及PTP在MAPK级联途径中的功能进行综述, 并着重介绍PTP在拟南芥中的研究进展。
- The results of transcription activity assays show that overexpression of WDR26 in COS7 cells can remarkably inhibit the transcription-stimulation activity of ELK-1 and SRE, which are downstream effectors of MAPK pathway. 转录活性分析显示在COS7细胞中WDR26蛋白过表达可以使MAPK信号途径的两个下游转录因子ELK-1和SRE的转录激活活性显著下降。
- To further explore the mechanism underlying interactions between pathogens and hosts' MAPK pathway, is of benefit to our understanding of nature as well as to our fight against pathogen infection. 简单介绍了MAPK信号通路的背景并详细总结了近几年关于病原菌如何作用于MAPK信号通路的研究工作,希望以此能够拓展对病原菌与宿主细胞作用方式的认识,深化对MAPK重要作用的了解。
- Two important cell signal pathways, JAK-STAT pathway and MAPK pathway, transfer the signals between regulators and hematopoietic relative genes. 两条主要的细胞信号转导通路,JAK-STAT通路和MAPK通路,介导调节调节因子对造血相关基因的活性调控。
- Keywords uveal melanoma;metastasis suppressor gene;MAPK pathway; 葡萄膜黑色素瘤;转移抑制基因;MAPK通路;
- Study of Recipe of DangGui BuXue Decoction on ox-LDL Activating p38 MAPK of Monocyte 当归补血汤对ox-LDL激活单核细胞p38MAPK的作用研究
- The role of p38 MAPK in LPS-induced ICAM-1 expression of vascular endothelial cells p38MAPK在LPS诱导血管内皮细胞ICAM-1表达中的作用
- P38 MAPK, PKC and PI3-K Mediate NADPH Oxidase Activation and Phagocytosis in Bovine PMN 牛多形核白细胞(PMN)中P38 MAPK,PKC和PI3-K介导的NADPH氧化酶激活和吞噬作用(英文)
- The Change of p38 MAPK Activation and the Effect on Morphology and Electrical Physiology in Rat Hippocampal Neuron Following Kainic Acid Administration 红藻氨酸对大鼠海马p38MAPK活性及海马神经细胞形态和电生理的影响
- They walked along the pathway toward the house. 他们沿著小路向那所房子走去。
- Keywords hematopoietic cell;micro-environment;hematopoietic-relative gene;JAK-STAT pathway;MAPK pathway; 造血细胞;骨髓微环境;造血相关基因;JAK-STAT通路;MAPK通路;
- The pathway was rough and covered with little stones. 这条路高低不平,铺满了小石头。