p21, cyclin E and CDK2 may be involved in the process of ginsenoside Rgl protection against t-BHP-induced senescence in WI-38 cells.

• 人参皂苷Rgl对抗三丁基过氧化氢对细胞衰老的诱导作用可能与其改变p21,cyclin E和CDK2的表达水平有关。