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- Cloning and prokaryotic expression of the ARQ genotype of ovine prion protein precursor gene 绵羊ARQ基因型PrP前体蛋白基因的克隆及原核表达
- ovine prion protein 绵羊朊病毒蛋白
- Although the wastewater generated from the experiment was clear of prion protein presence, the biosolids were not. 虽然实验产生的废水中没有朊病毒出现,但废水处理产生的污泥却并非如此。
- Complementary DNA (cDNA) sequence of Japanese sea bass (Lateolabrax japonicus) prion protein (PrP) encoding gene was cloned and characterized through RT-PCR approach. 采用RT-PCR方法分离了鲈鱼蛋白质感染因子蛋白编码基因序列,并进行了结构分析。
- In this article, we will introduce mad cow disease, prion protein, transmissible spongiform encephalopathy, and Creutzfeldt-Jakob disease (CJD). 本篇文章即由狂牛症著手,浅谈普利旺蛋白质、传染性海绵状脑病变、库贾氏病。
- Conclusion Prion protein 106-126 peptide can induce apoptosis in differentiated PC12 cells and present cellular toxicity definitely. 结论:朊蛋白106-126肽段能够诱导分化后的PC12细胞凋亡,具有明确的毒性作用。
- However, the prion protein in scrapie-infected brain tissue differs from normal prion protein in some of its properties. 然而,在感染羊瘙痒病的大脑组织的普利昂蛋白在某些性质上不同于一般的普利昂蛋白。
- This paper reviews the basic feature,chemical structure of prion protein and prion disease,plausible physical functions of PrPc. 介绍了朊病毒的基本特征、化学结构以及可能具有的生理功能:参与神经系统功能的维持;
- However, other scientists are skeptical and believe that the prion protein is a viral coat protein that protects a small nucleic acid that has not yet been detected. 然而,另外的科学家表示怀疑,他们相信普利昂蛋白是病毒中用于保护至今还未被检测到小核酸的衣壳蛋白。
- Propagation of transmissible spongiform encephalopathies is believed to involve the conversion of the cellular prion protein, PrPC, into a misfolded oligomeric form,PrPSc. 长久以来,系统生物学研究的终极目标在于理解生物体内部机制的运作,以获得所需的重要资讯并建构模型工具。
- The prion protein(PRNP) genes of 25 Amur tigers were amplified by PCR using primers designed from mammalian PRNP. These PCR products contain 402 bp encoding 134 amino acids,and have a homology of 99.67%. 根据已报道的哺乳动物朊病毒基因序列设计引物;采用PCR方法扩增了25只东北虎的朊病毒基因;克隆、测序及序列分析表明;所得到的东北虎朊病毒基因片段为402bp;编码134个氨基酸的前体蛋白;核苷酸序列同源性为99.;67%25。
- Although some are already at work to develop drugs that target the prion protein, these programmes target the infectious form of the protein and may not be useful in warding off Alzheimer's disease. 他是加利福尼亚,三藩市神经疾病研究院格拉斯通学院的神经专家。尽管有人已经在研究针对朊蛋白的药物,但是仅针对感染型的朊蛋白可能对于治疗阿尔茨海默病没有太大的作用。
- A transmissible spongiform encephalopathy of cattle associated with abnormal prion proteins in the brain. 牛海绵状脑病是一种可以在牛中传播的海绵状脑病,与脑组织中异常朊病毒蛋白有关。
- What is een more peculiar: exactly the same prion proteins occur in healthy animals. 更奇特的是:这种蛋白质在健康动物中也存在。
- As prion proteins multiply, they accumulate within nerve cells, destroying them and eventually causing Brain tissue to become riddled with holes. 随着普利子蛋白质复制,它们积聚在神经细胞里,破坏细胞最终使脑组织变得布满孔洞。
- Distribution of prion protein in cow reproductive system 朊蛋白在奶牛生殖系统表达的定位
- Cloning and sequence analysis of prion protein gene in African lion 非洲狮朊蛋白基因的克隆与序列分析
- In mice inoculated with prions in the gut and then given antibodies directed against prion proteins, the incubation period was prolonged. 若将普恩蛋白注入小鼠的肠道,然后再给予针对普恩蛋白的抗体,则潜伏期会延长。
- Doesn't ovine wolf eat on the world? 世界上有没有不吃羊的狼?”
- You need more protein to build you up. 你需要增加蛋白质以增强体质。