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- Objective To study the reinforcing effect of the nucleus accumbens and ventral pallidum in rats. 目的探讨伏隔核和腹侧苍白球在药物强化中的作用。
- Opiates can also generate a strong “reward” message by acting directly on the nucleus accumbens. 鸦片类物质还会直接作用在依核上,产生一种强烈的报偿讯号。
- Title: Study on decision-making alternation after bilateral nucleus accumbens ablation in drug addicts. 关键词:立体定向手术;伏隔核;药物依赖;赌博任务测验;行为选择
- Local alpha-bungarotoxin-sensitive nicotinic receptors in the nucleus accumbens modulate nicotine-stimulated dopamine secretion in vivo. 伏隔核中的局部阿尔法-金环蛇毒素敏感烟碱感受器在体调制烟碱诱发多巴胺分泌。
- Underweight rats have enhanced dopamine release and blunted acetylcholine response in the nucleus accumbens while bingeing on sucrose. 体重过轻大鼠在狂饮蔗糖时可使伏隔核内多巴胺释放增加并且使乙酰胆碱反应变迟钝。
- Objective :To study the influence of 6 hydroxydopamine(6 OHDA)lesions of the nucleus accumbens(NAc) on the dihydroetorphine(DHE)rewarding effect. 目的:研究伏隔核(NAc)中多巴胺(DA)神经末梢在二氢埃托啡(DHE)精神依赖性中的作用。
- Objective To study the effects of haloperidol(HAL) on electric stimulated dopamine(DA) release from rat nucleus accumbens(Acb). 目的研究氟哌啶醇(HAL)对大鼠伏核多巴胺(DA)释放的影响。
- Behavioal studies indicate that nucleus accumbens (NAcc) is a key brain area forthe rewarding effects of opiate and for opiate addiction. 行为学研究指出,伏核是阿片奖赏作用(reward effect),和阿片成瘾的关键脑区域。
- "Nucleus Accumbens" is also known as "nucleus accumbens septi", which is the key part that can lead the brain to feel happy. “阿肯伯氏核”又称伏核,是大脑体验愉悦感的关键部位。
- R.I. scans show that when people are shopping, the nucleus accumbens, a seat of pleasure in the brain, lights up, as does the insula, a pain center. 核磁共振成像的扫描结果表明,人们在购物时,大脑中控制愉悦的所在地伏隔核和痛苦中心脑岛都会兴奋起来。
- Stereotactic lesioning of bilateral nucleus accumbens can greatly alleviate not only the opioid psychic dependence,but also the alcohol and nicotine dependence. 针对阿片类药物依赖病人实施的伏隔核毁损术不但能明显降低吸毒者阿片类药物的心理依赖程度,而且对酒精及尼古丁依赖也有明显的抑制作用。
- When drugs of abuse increase dopamine release from the VTA into the nucleus accumbens, they also alter the responsiveness of the VTA and nucleus accumbens to glutamate for days. 当滥用药物促使VTA释出较多的多巴胺到依核时,也会改变VTA与依核对麸胺酸的反应达数天之久。
- Ferris found that activity in the mother's nucleus accumbens, a site that is integral to reinforcement and reward, increased significantly when she nursed her pups. 费瑞斯发现,脑中对行为强化和报偿极为重要的依核,在母鼠喂奶时活性明显增强。
- The answer is that all drugs of abuse, in addition to any other effects, cause the nucleus accumbens to receive a flood of dopamine and sometimes also dopamine-mimicking signals. 答案是,除了其他作用之外,所有的滥用药物都会让依核接受到大量的多巴胺,有时还有假的多巴胺信号。
- Each of these systems has overlapping projections to the nucleus accumbens, where these inputs are integrated under the modulatory influence of dopamine. 这些区域向伏隔核的投射有重叠,在伏隔核受多巴胺影响调制。
- Further experiments showed that dopamine restructured a part of the vole's brain called the nucleus accumbens, a region that many animals have, including humans. 进一步的试验表明多巴胺改变了田鼠大脑中被称为伏隔核的区域,包括人类在内的许多动物都有这个区域。
- Results The nucleus accumbens lesion led to an extinction of the place preference for heroine-paired environment in rats and the anterior cingulate cortex... 结论伏隔核和扣带回是调节强化作用的重要位置;本实验为阐明药物依赖机制及指导临床药物依赖的治疗提供一定的参考。
- Their studies concentrated on a brain area known as the nucleus accumbens (NAC), a region deep in the brain, known to play a role in expectation of reward. 小组的研究主要针对一个被称为伏隔核(NAC)的大脑深处区域,NAC在奖励期待过程中起着重要作用。
- Nucleus accumbens, an important component of brain-reward regions, is involved in the reinforcement, tolerance, addiction and expression of withdrawal syndrome of drug addiction. 伏核是脑奖赏中枢的重要组成部分,参与成瘾药物的强化、耐受、成瘾过程及药物戒断综合征的表达。
- Objective To observe the effects of nucleus accumbens lesion in Methamphetamine (MAP) rats on behavior and the expression of Dopamine Receptor D_2 (DRD_2) in special areas of brain through stereotactic technique. 目的探讨立体定向伏隔核毁损对甲基苯丙胺(MAP)模型大鼠行为学及不同脑区多巴胺D2受体表达的影响。