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- Guided by the nuclear localization sequence, almost all PAI-2 mutants entered nuclei, while wide type PAI-2 distributed evenly in the cytoplasm and nucleus. 结果提示在核定位序列的引导下,几乎所有的PAI-2都进入了细胞核,而野生型PAI-2则弥散分布于HeLa细胞内。
- nuclear localization sequence(NLS) 一段核定位序列
- Keywords Parathyroid hormone related peptide;nuclear localization sequence;C-terminus;brain development;gene knock in mouse model; 甲状旁腺素相关肽;核定位序列;C-末端;脑发育;基因敲入小鼠模型;
- nuclear localization sequence 核定位系列
- nuclear localization signal sequence 核定位信号顺序
- CBF3 gene contains a nuclear localization signal domain (NLS) and an acidic region. CBF3包含一个核定位信号(NLS)域和一个酸性域。
- The results showed that formation of cis proline was significantly related to the local sequence and amino acid component. 结果表明,脯氨酸采取顺式还是反式构象与其局部的序列以及整条肽链的氨基酸组分均有较强的关联。
- But the TCP domain itself could not confer the nuclear localization because the chimeric proteins with TCP domain alone were dispersed all over the transformed cells. TCP结构域自身不能完成核定位过程;还需要结构域两侧旁邻氨基酸序列的协助.
- The received signal is multiplied by the local sequence, and then the proposed scheme achieves the M-ary despread spectrum and OFDM demodulation at the same time. 在将基站接收信号分别与各用户原型扩频码镜像序列的OFDM调制结果相乘后,利用OFDM解调器可同时完成M元解扩和多载波解调。
- We show here that Plasmodium uses a PEXEL/VTS motif to introduce the circumsporozoite (CS) protein into the hepatocyte cytoplasm and a nuclear localization signal (NLS) to enter its nucleus. 本文中我们发现疟原虫使用PEXEL/VTS基序介导环化孢子蛋白CS进入肝实质细胞质并促使核定位信号(NLS)进入细胞核中。
- EMF-like gene contains an open reading frame of 1881bp encoding a putative transcription factor of 626 amino acids, which possessed of a C2H2-type zinc finger motif, two putative nuclear localization signals and an acidic cluster. 推测新克隆的基因序列含有完整的1881bp的开放阅读框,编码一条约71kD的多肽,包含626个氨基酸残基,编码的蛋白质有一个C_2H_2型锌指结构区,两个核定位信号区和一个酸性区,可能是一个转录因子。
- Objective To find the peptides that have strong binding ability to the nuclear localization signals (NLS) of human Cytomegalovirus (HCMV) PPUL44 protein, and to analyze their amino acid sequences. 目的 寻找与人巨细胞病毒 (HCMV)PPUL44蛋白核定位信号 (NLS)具有较强结合能力的多肽 ,研究这些多肽的氨基酸序列特点。
- In conclusion, LIM domain 2 at the C-terminus of hhLIM plays a central role in F-actin polymerization and cytoskeleton stabilization, whereas the first LIM domain is essential for the nuclear localization of hhLIM. 结果表明;LIM结构域2在hhLIM与actin相互作用及调节actin细胞骨架组构中起决定性作用.
- Together with the repeats is heptad repeats,resemblingleucine zippers. Three functional nuclear localization signals (NLSs) and an acidicactivation domain (AAD) are also found in the C-terminal region. C-端有 3 个核定位信号(Nuclear localization signals, NLSs)和 1 个酸性转录激活域(Acidic transcriptional activation domain, AAD)。
- Abstract: Objective: To structurally analyse and functionally identify the nuclear localization signal(NLS) in BRD7 and then study its effect on the subcellular localization of BRD7. 摘 要: 目的:对BRD7的核定位信号进行预测、结构分析和功能鉴定,并考察其对BRD7亚细胞定位的影响。
- Although no typical nuclear localization signals were found in MOC1, the MOC1::GFP fusion protein was localized into the nuclear. 虽然没有发现典型的核定位信号序列,但是MOC1:GFP的融合蛋白却定位在了细胞核内。
- The most important was that wild BRD7 localized in nucleus, whereas NLS-deleted BRD7 shifted the nuclear localization to be mostly in cytoplasm. 同时发现野生型BRD7呈胞核分布,而核定位信号缺失型BRD7主要呈胞浆分布。
- A new nuclear power station is on the stocks here. 这座新的核电站在建造之中。
- This old man is a famous nuclear physicist. 这位老人是一位著名的核物理学家。
- Plans for nuclear plants have been declassified. 建造核装备的计划已不再保密。